Differential Diagnosis in Dermatopathology

Lymphocytoma cutis with lymphoid follicles vs. Follicular-cell lymphoma

…e usually occurs as a solitary, rapidly growing tumor. Most of the neoplastic lymphocytes express the CD30 antigen. Panniculitis-like T-cell lymphoma is a distinct type derived from activated cytotoxic T-cells and characterized by plaques and subcuta…

Histologic Diagnosis of Inflammatory Skin Diseases

Adult T-cell leukemia/lymphoma

…e usually occurs as a solitary, rapidly growing tumor. Most of the neoplastic lymphocytes express the CD30 antigen. Panniculitis-like T-cell lymphoma is a distinct type derived from activated cytotoxic T-cells and characterized by plaques and subcuta…

A Clinical Atlas of 101 Common Skin Diseases

Lymphomatoid Papulosis

A distinctive type of CD 30 lymphoma characterized by the presence mostly of papules, some of them purpuric, that may ulcerate and heal with a scar, and by lesions that tend to come and go for years, eventually disappearing entirely or, on occasion,…

A Clinical Atlas of 101 Common Skin Diseases

Mycosis Fungoides

A systemic lymphoma of T-lymphocytes that manifests itself first in the skin as macules and then patches that often are scaly. Most people with the disease have only scaly macules and patches for a lifetime, but some patients may develop papules, pl…

Therapeutic Strategies in Dermatology

Dermatitis Herpetiformis: Treatment

…etiformis should be reevaluated in patients who do not respond to appropriately administered sulfone therapy, as a rapid response is almost universal. Patients with dermatitis herpetiformis are at increased risk to develop lymphoma of the GI tract. A…

Therapeutic Strategies in Dermatology

Dermatitis Herpetiformis: Key Points

…stemic corticosteroids are of little value in DH. In addition, there are other autoimmune conditions associated with DH, most commonly hypothyroidism, as well as an increased risk of non-Hodgkin lymphoma, specifically bowel-associated T cell lymphoma

Therapeutic Strategies in Dermatology

Erythema Annulare Centrifugum: Overview

…umented infection, will lead to resolution. Pitfalls Failure to evaluate and re-evaluate for an underlying cause may result in persistence of the cutaneous reaction. Lupus erythematosus, sarcoidosis, syphilis, and rarely cutaneous T cell lymphoma m…

Therapeutic Strategies in Dermatology

Palmar and Plantar Keratoderma: Overview

…ratodermas (PPK) can occur as a primary, inherited disorder of the volar surfaces, or as part of a generalized disorder, such as psoriasis, cutaneous T-cell lymphoma, or ichthyosis. Discussion of treatment here is limited to inherited forms only. Tre…