Search Results for: suppuration

Differential Diagnosis in Dermatopathology

Acne vulgaris, erythematous papule vs. Rosacea, erythematous papule

Infection of skin and subcutaneous tissue by atypical mycobacteria, that is, mycobacteria other than those responsible for tuberculosis and leprosy, expressed clinically as keratotic and crusted papules, plaques, nodules, and tumors that may be…

Histologic Diagnosis of Inflammatory Skin Diseases

Acne vulgaris

…, Propionibacterium acnes, Pityrosporum ovale and Pityrosporum orbiculare, and Demodex folliculorum. That happening provokes suppuration, which is followed by granulomatous inflammation and, eventually, by fibrosis. When fibrosis is extensive, the…

Histologic Diagnosis of Inflammatory Skin Diseases

Our Definition of “Inflammation” and “Inflammatory Disease”

…istiocytes and later fibrocytes. A caricature of that phenomenon is what follows on rupture of an infundibular cyst, namely, suppuration, granulomatous infiltration, and fibrosis; of course, a plug of corneocytes in an infundibulum and a bolus of…

Histologic Diagnosis of Inflammatory Skin Diseases

Rosacea

…ociated with lymphocytes in infundibula Fully developed Perivascular infiltrates of lymphocytes and, sometimes, plasma cells Suppuration in some infundibula Well-circumscribed collections of epithelioid histiocytes, usually in peri-infundibular…

Multiple confluent reddish nodules

Multiple confluent reddish nodules

…lged epidermis (grenz zone). In contrast to other cutaneous/subcutaneous and deep mycoses, there are no areas of necrosis or suppuration, nor pseudocarcinomatous hyperplasia of the epidermis, unless the biopsy is taken at the edges of an ulcer. The…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…uch earlier stage, sebaceous glands were more numerous and infundibular cysts were even more formidable. The cysts ruptured, suppuration and granulomatous inflammation ensued, and fibrosis, seen here, followed. In short, rhinophyma begins with…

Histologic Diagnosis of Inflammatory Skin Diseases

Collagen

…the skin, e.g., those that occur secondary to trauma, such as scars, keloids, and dermatofibromas; those marked by extensive suppuration and subsequent degeneration of collagen, such as ruptured epidermal (infundibular) and follicular…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ry to a suppurative infundibulitis. In some lesions of Behçet’s disease, however, especially those situated on a face, suppuration is centered in and around infundibula. 10.8.2A: Vasculitis, small vessel, neutrophilic + 10.8.2B: Dense…

Differential Diagnosis in Dermatopathology

Discussions

…houses a thrombus and is situated in a septum in the subcutaneous fat Coagulation necrosis of adipocytes in conjunction with suppuration in lobules. Later clinical lesions of nodular vasculitis are dusky nodules that ulcerate and heal with…