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Histologic Diagnosis of Inflammatory Skin Diseases

Telogen effluvium

…ss of hair on the scalp, especially from the parietal region; alopecia sometimes subtle and hardly evident clinically Individual lesions None in skin itself Course Months, with eventual return to normal pelage Differential diagnosis clinical Androg…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

…; urticaria, is wholly artificial and bereft of logic. Error: Alopecia mucinosa manifests itself in two different ways, namely, as an inflammatory process on one hand and as mycosis fungoides on the other, the former sometimes “converting&#8221…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Telogen Effluvium—An Inflammatory Disease?

…oes not result in striking baldness. Only occasionally is the alopecia restricted clinically to a specific area (such as the occiput in newborns) or is distributed diffusely. But Kligman did not make clear whether he considered the process to be phys…

Differential Diagnosis in Dermatopathology

Discussions

…e as baffling and frustrating to dermatopathologists than the alopecias. Those aberrations are rivaled in difficulty only by diseases of nail units. Why do those subjects prove to be so recondite? Because biopsies of alopecias and disorders of nail u…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ate of small lymphocytes and eosinophils = Mycosis fungoides, alopecia mucinosa expression  The infiltrate is present not only in the dermis, but also in infundibula and follicles, both of which house deposits of mucin. Infundibula are dilated and pl…

Histologic Diagnosis of Inflammatory Skin Diseases

Trichotillomania

…twists hairs back and forth Differential diagnosis clinical Alopecia areata consists of well-defined patches of complete hair loss. Tinea capitis is usually associated with scales, crusts, or pustules. Findings histopathologic Fully developed Cru…

Differential Diagnosis in Dermatopathology

Discussions

Alopecia areata and trichotillomania have several attributes histopathologic in common, namely, some follicles in catagen and often in telogen, long fibrous tracks behind shortened follicles and, in sections from some specimens, and hardly any periv…

Differential Diagnosis in Dermatopathology

Discussions

The alopecias of discoid lupus erythematosus and of lichen planus share several findings histopathologic, among them being perivascular, peri-infundibular, and perifollicular infiltrates of lymphocytes, vacuolar alteration at the junction between in…

Histologic Diagnosis of Inflammatory Skin Diseases

Hair Follicles

…ar. Epithelial mucinosis is the sine qua non for diagnosis of alopecia mucinosa, which is but one of many variants morphologic of mycosis fungoides. Epithelial mucinosis also is encountered often in “folliculitis” with eosinophils (badly…

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