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Differential Diagnosis in Dermatopathology

Discussions

…re as baffling and frustrating to dermatopathologists than the alopecias. Those aberrations are rivaled in difficulty only by diseases of nail units. Why do those subjects prove to be so recondite? Because biopsies of alopecias and disorders of nail…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…and in an infundibulum replete with mucin = Mycosis fungoides, alopecia mucinosa expression  Epithelial mucinosis is the sine qua non for diagnosis of the alopecia mucinosa expression of mycosis fungoides, but diagnosis of that lymphoma is not depend…

Differential Diagnosis in Dermatopathology

Discussions

…lichen planus, known as lichen planopilaris, that eventuate in alopecia, begin as violaceous macules that rapidly become papules that soon are keratotic. In the course of many months, they evolve into atrophic scars devoid of hairs. The scarring alop…

Differential Diagnosis in Dermatopathology

Discussions

Alopecia areata and trichotillomania have several attributes histopathologic in common, namely, some follicles in catagen and often in telogen, long fibrous tracks behind shortened follicles and, in sections from some specimens, and hardly any periv…

Histologic Diagnosis of Inflammatory Skin Diseases

Trichotillomania

…ecimen. When, however, trichomalacia is seen in the context of alopecia, the diagnosis is almost certainly trichotillomania. Episodically, persons with alopecia areata twist hairs that remain behind, so a particular section may show findings characte…

Histologic Diagnosis of Inflammatory Skin Diseases

Hair Follicles

…effects of products of lymphocytes, the result being permanent alopecia. One inflammatory type of alopecia is characterized by infiltrates of lymphocytes solely around the follicular bulb, i.e., alopecia areata and its variants, to wit, alopecia tota…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ositioned in the upper part of the subcutaneous fat = Traction alopecia  Like androgenetic alopecia, telogen effluvium, and trichotillomania, traction alopecia is a specific type of hair loss that first is affiliated with prominent lichenoid infiltra…

Histologic Diagnosis of Inflammatory Skin Diseases

Syphilis

…discoid lupus erythematosus, lichen planopilaris, and traction alopecia in which infiltrates of lymphocytes tend to destroy infundibula and follicles, resulting in permanent alopecia, infiltrates of inflammatory cells in secondary syphilis cause invo…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…, and hyperkeratosis = Lupus erythematosus, discoid, permanent alopecia  A marked decrease in number of terminal follicles in this specimen taken from a scalp indicates that the alopecia is permanent. The other changes, especially those at the dermoe…

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