Search Results for: alpha-1 antitrypsin deficiency

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Histologic Diagnosis of Inflammatory Skin Diseases

Acrodermatitis enteropathica

…ure to thrive and disturbances of mentation. Nutritional zinc deficiency, e.g., in premature infants, patients with parenteral nutrition, inflammatory bowel disease. Differential diagnosis clinical Hartnup’s disease, methylmalon acidemia, propi…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Churg-Strauss Granuloma and Allergic Granulomatosis?

…re the issue is often debated hotly (akin to that of Kyrle’s disease and the panniculitis ostensibly caused by a1 antitrypsin deficiency). If the essential character of allergic granulomatosis will remain forever speculation, as in reality is t…

Clinical Case Studies

About the Editors

…frey S. Dover, M.D., FRCPC Dr. Dover is one of the country’s preeminent academic dermatologists and a leader in the fields of dermatology, laser medicine and cosmetic surgery. Dr. Dover graduated as the silver medalist, magna cum laude with an…

Histologic Diagnosis of Inflammatory Skin Diseases

Suggested Readings

…opic dermatitis or bronchial asthma. Int Arch Allergy Immunol 1996;110:261-271. Mast Cells Ackermann L, Harvima IT. Mast cells of psoriatic and atopic dermatitis skin are positive for TNF-alpha and their degranulation is associated with expression of…

Histologic Diagnosis of Inflammatory Skin Diseases

Suggested Readings

…junction using electron microscopy. J Dermatol Sci 2003;32:231-235. Kivirikko S, McGrath JA, Baudoin C, et al. A homozygous nonsense mutation in the alpha 3 chain gene of laminin 5 (LAMA3) in lethal (Herlitz) junctional epidermolysis bullosa. Hum Mo…

Histologic Diagnosis of Inflammatory Skin Diseases

Cells That Mediate Inflammation (Inflammatory Cells)

…ation for them is “cells of an inflammatory process”; the cells themselves are not inflammatory. For convenience and because of convention, we refer to them, nonetheless, as inflammatory cells. The mere presence of inflammatory cells, how…

Histologic Diagnosis of Inflammatory Skin Diseases

Necrolytic migratory erythema

…d with the disorder. Differential diagnosis clinical Acquired deficiency of zinc may occur in persons who suffer from alcoholism, hepatic disease, or malnutrition, but levels of glucagon in those persons are not elevated. Correlation clinicopathologi…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Ichthyoses?

…y the editors of The Archives of Dermatology to be one of the 100 most important publications in the first 100 years of that journal. Curiously, Frost and Van Scott failed to define ichthyosis—and the result of that deficiency was inevitable, i.e., c…

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