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Histologic Diagnosis of Inflammatory Skin Diseases

Acrodermatitis enteropathica

Acrodermatitis enteropathica Synonyms Zinc deficiency Presentation stereotypical Age and sex Infants of both sexes who suffer from an inherited deficiency of zinc; may occur in adults; characterized in infants by a triad of acral dermatitis, alopeci…

Histologic Diagnosis of Inflammatory Skin Diseases

Suggested Readings

…ecular Biology of the Skin. New York: Oxford University Press, 1991. Kupper TS. Immune and inflammatory processes in cutaneous tissues: mechanisms and speculations. J Clin Invest 1990;86:1783-1789. Lambert RW, Granstein RD. Neuropeptides and Langerha…

Histologic Diagnosis of Inflammatory Skin Diseases

Suggested Readings

…hanced expression in fibrotic skin diseases. J Invest Dermatol 1999;113:246-250. Burgeson RE. Type VII collagen, anchoring fibrils, and epidermolysis bullosa. J Invest Dermatol 1993;101:252-255. Ghohestani RF, Hudson BG, Claudy A, Uitto J. The alpha

Histologic Diagnosis of Inflammatory Skin Diseases

Cells That Mediate Inflammation (Inflammatory Cells)

…polymorphonuclear leukocytes, maturing thus over the course of 10 days. Mature neutrophils then enter the bloodstream, where they circulate for approximately 7 to 10 hours before departing for extravascular tissues, spending there their autumnal hour…

Clinical Case Studies

About the Editors

…n of dermatology both nationally and internationally. He is an Alpha Omega Alpha Honor Society graduate of Yale University School of Medicine and trained in dermatology at the Massachusetts General Hospital and the Department of Dermatology at Harvar…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Ichthyoses?

…by the editors of The Archives of Dermatology to be one of the 100 most important publications in the first 100 years of that journal. Curiously, Frost and Van Scott failed to define ichthyosis—and the result of that deficiency was inevitable, i.e.,…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.18.1A: Perivascular dermatitis, slightly psoriasiform + 10.18.1B: Mixed-cell infiltrate with pallor in the upper part of the viable epidermis in company with scale-crust = Necrolytic migratory erythema Findings identical with th…

Histologic Diagnosis of Inflammatory Skin Diseases

Necrolytic migratory erythema

Necrolytic migratory erythema Synonyms Erythema necroticans migrans Glucagonoma syndrome Pseudoglucagonoma syndrome Presentation stereotypical Age and sex Middle-aged or elderly persons of both sexes with increased levels of serum glucagon Distrib…

Erythema in Rosacea

Erythema in Rosacea

…d on its long-term use for glaucoma.  It is a highly selective alpha-2-adrenergic receptor agonist with vasoconstrictive properties with onset of action as quickly as 30 minutes, peak efficacy at 4-6 hours, and duration of effect for 12 hours.  In in…

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