Dermatology Practical & Conceptual

An itching plaque

…contacting the elastic band of the underwear under the right breast (Figure 1). The remaining physical exam showed no other relevant lesions. Figure 1. A brownish papule or plaque contacting the elastic band of the underwear under the right breas…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Scleroderma?

…rome, toxic oil syndrome, exposure to polyvinyl chloride, and breast implants of silicone Diseases that are identical to one another clinically and histopathologically are not necessarily identical in terms of cause, mechanism, or biologic behavio…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Sclerotic Fibroma?

…with metastases of some carcinomas, especially those from the breast to skin. Sclerotic fibroma is not a specific disease, but a distinctive pattern of connective tissue that is initiated by more than one cause, ranging from papillomavirus in Cowden&…

Differential Diagnosis in Dermatopathology

Angiolymphoid hyperplasia with eosinophilia vs. Angiosarcoma

A malignant neoplasm of melanocytes that, in the skin, begins as a macule and may become a patch or a papule. A flat lesion of melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly…

Differential Diagnosis in Dermatopathology

Nevus verrucosus vs. Acanthosis nigricans

A malignant neoplasm of melanocytes that, in the skin, begins as a macule and may become a patch or a papule. A flat lesion of melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly…

Differential Diagnosis in Dermatopathology

Syringocystadenoma papilliferum vs. Hidradenoma papilliferum

A malignant neoplasm of melanocytes that, in the skin, begins as a macule and may become a patch or a papule. A flat lesion of melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly…

Differential Diagnosis in Dermatopathology

Ichthyosis vulgaris vs. X-linked ichthyosis

A malignant neoplasm of melanocytes that, in the skin, begins as a macule and may become a patch or a papule. A flat lesion of melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly…