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Histologic Diagnosis of Inflammatory Skin Diseases

Parasitic infestations

…nds, e.g., secondary to rupture of infundibular or follicular cysts, do not exhibit parasites in their midst. Clue to specific diagnosis histopathologic “Flame figures” is a clue to a variety of diseases marked by innumerable eosinophils…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Tricho-, pilo-, folliculo- ?

…. If a student is to understand the real nature of follicular cysts, hamartomas, and neoplasms, it is essential that differences be appreciated between the names of those lesions, on one hand, and the actual character of them, on the other. A first s…

Histologic Diagnosis of Inflammatory Skin Diseases

Collagen

…red epidermal (infundibular) and follicular (isthmus-catagen) cysts, deep fungal infections and atypical mycobacterial infections, and pyoderma gangrenosum; and those typified by long-standing lichenoid infiltrates of lymphocytes, such as lichen plan…

Histologic Diagnosis of Inflammatory Skin Diseases

Phaeohyphomycosis

…ess, and fever. Abscesses caused by rupture of infundibular cysts are associated with signs of inflammation, but no symptoms systemic. Findings histopathologic Fully developed Subcutaneous abscess Histiocytes, some of them multinucleate, and lym…

Differential Diagnosis in Dermatopathology

Discussions

…fundibular rete ridges of dilated pore are devoid of ducts or cysts, whereas the lobules of pilar sheath acanthoma usually contain structures like sebaceous ducts and cysts that house cornified cells. Last, dilated pore shows no evidence of follicula…

Histologic Diagnosis of Inflammatory Skin Diseases

Porphyria cutanea tarda

…n the upper part of the dermis Milia, i.e., tiny infundibular cysts, in some lesions Re-epithelialization of epidermis beneath a subepidermal blister Correlation clinicopathologic The vesicles are subepidermal. Milia develop consequent to an impedim…

Differential Diagnosis in Dermatopathology

Metastatic carcinoma from a breast vs. Morpheiform basal-cell carcinoma

…solely as noninflammatory lesions, i.e., comedones and intact cysts, or as inflammatory lesions, i.e., papules, nodules, and pustules. The process may resolve without residua or with scars of different types, e.g., keloidal or atrophic, including cri…

Differential Diagnosis in Dermatopathology

Discussions

…te follicular germs. In early lesions, no infundibular “cysts” are present in the basal-cell carcinoma; fully-developed lesions, however, are marked by numerous tiny infundibular cyst-like structures. That infundibulocystic basal-cell car…

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