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Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Tricho-, pilo-, folliculo- ?

“pilo- [L. pilus]. Combining form indicating hair. . . . tricho- [Gr. thrix, trichas, hair]. A prefix denoting a relationship to hair. . . . follicle- [L. folliculus, little bag]. A small secretory sac or cavity.” Tabers Cyclopedic Me…

Histologic Diagnosis of Inflammatory Skin Diseases

Parasitic infestations

Parasitic infestations Presentation stereotypical Age and sex No predilection for age or sex; occurring chiefly in the tropics Distribution of lesions Localized usually to one site anatomic; some infestations parasitic are associated with lesions wi…

Histologic Diagnosis of Inflammatory Skin Diseases

Collagen

More than 70% of the dry weight of the normal dermis consists of collagen (Fig. 1.79). The major collagens are Type I and Type III. Type I collagen has a molecular mass of about 290 KDa and accounts for approximately 80% of the total amount of colla…

Differential Diagnosis in Dermatopathology

Discussions

…nfundibular rete ridges of dilated pore are devoid of ducts or cysts, whereas the lobules of pilar sheath acanthoma usually contain structures like sebaceous ducts and cysts that house cornified cells. Last, dilated pore shows no evidence of follicul…

Histologic Diagnosis of Inflammatory Skin Diseases

Porphyria cutanea tarda

Porphyria cutanea tarda Presentation stereotypical Age and sex Young and middle-aged adults of both sexes, but mainly women taking estrogens or who are alcoholic Distribution of lesions Blisters on dorsa of hands and feet, pigmentary alterations and…

Differential Diagnosis in Dermatopathology

Metastatic carcinoma from a breast vs. Morpheiform basal-cell carcinoma

A hamartoma of epidermis, epithelial structures of adnexa, and presumably dermal elements, typified, when fully formed, by a papillated or verrucous yellowish plaque situated usually on the scalp. The condition may present itself as a solitary lesio…

Differential Diagnosis in Dermatopathology

Discussions

Trichoepithelioma and infundibulocystic basal-cell carcinoma have many features in common, including relative symmetry, follicular differentiation, elements of both basaloid (trichoblastic) and squamoid (spinous) cells, necrotic neoplastic cells, mi…

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