Search Results for: diffuse neuroendocrine system (anachronistic)

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Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Verruciform Xanthoma?

…ase report and immunohistochemical study. J Cutan Pathol 1993;20(1):84–86. “We report an HIV–I+ patient with diffuse psoriasiform skin lesions that showed histologic changes of verruciform xanthoma.” Smith KJ, Skelton HG,…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…of the angle at which they were transected by a blade of a microtome, i.e., the foamy cytoplasm was not sampled. 10.114.2A: Diffuse dermatitis, granulomatous + 10.114.2B: Foamy histiocytes, some of them multinucleate, and a sprinkling of…

When all you have is a dermatoscope—start looking at the nails

When all you have is a dermatoscope—start looking at the nails

…gure 15. Nail alteration after chemotherapy with docetaxel. (A) Overview. (B) Dermatoscopy. The dermatoscopic view reveals a diffuse yellow-red discoloration of multiple nails indicative of an increased vascularization of the nail matrix and a…

Histologic Diagnosis of Inflammatory Skin Diseases

Rheumatoid neutrophilic dermatitis

…Marked edema of the papillary dermis Correlation clinicopathologic Papules and nodules result from a combination of a dense diffuse infiltrate of neutrophils throughout much of the reticular dermis and prominent edema of the papillary dermis….

Blue nevus with a starburst pattern on dermoscopy

Blue nevus with a starburst pattern on dermoscopy

…esion was excised under the diagnosis of a blue nevus. Histological examination revealed spindle cells with melanin pigments diffusely present in the upper dermis and around hair follicles in the mid-dermis, but not in the epidermis. The melanocytic…

Incidental Merkel cell carcinoma in a cutaneous horn: a case report

Incidental Merkel cell carcinoma in a cutaneous horn: a case report

…ich likely derive from the neural crest, are basally located skin cells believed to function in mechano-reception and/or the neuroendocrine system. Merkel cell carcinoma (MCC), is a rare cutaneous malignancy first described in 1972 by Toker [1]….

Histologic Diagnosis of Inflammatory Skin Diseases

Lymphedema

…more than men Distribution of lesions Distal extremities, legs more than arms; genitalia episodically Arrangement of lesions Diffuse involvement of parts, e.g., elephantiasis Individual lesions Verrucous hyperkeratotic papules and plaques Course…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.16.1A: Diffuse dermatitis, granulomatous and fibrosing + 10.16.1B: Purple intranuclear and intracytoplasmic inclusions in a fibrocyte = Cytomegalic inclusion disease The attributes cytopathologic of cytomegalic inclusion disease pictured…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.7.1A: Diffuse dermatitis, mixed-cell + 10.7.1B: Proliferation of venules lined by plump endothelial cells, a sprinkling of neutrophils and nuclear “dust” of neutrophils, and clumps of granular violaceous material = Bacillary…

Histologic Diagnosis of Inflammatory Skin Diseases

Predominantly Intraepithelial Fluorescence

…antibodies to IgA, rather than to IgG. Only one other intraepithelial pattern of fluorescence is of significance and that is diffuse, somewhat coarse, granularity present throughout the epithelium (often most evident in the lower half of the…

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