Differential Diagnosis in Dermatopathology

Nevus verrucosus vs. Acanthosis nigricans

Epidermal nevi are hamartomas in which the epidermis is abnormal, being hyperkeratotic, and in which lesions are aligned along Blaschko’s lines….

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Churg-Strauss Granuloma and Allergic Granulomatosis?

“The occurrence of a clinical syndrome of severe asthma, fever, and hypereosinophilia, together with symptoms of vascular embarrassment in various organ systems, has been established. . . . The basic anatomical changes . . . consisted of wide…

Differential Diagnosis in Dermatopathology

Discussions

Nevus verrucosus and acanthosis nigricans are processes that affect the papillary dermis and the epidermis. Both conditions may display hyperkeratosis, epidermal hyperpigmentation, papillomatosis, melanophages, and an increased number of fibrocytes…

Differential Diagnosis in Dermatopathology

Discussions

Porokeratotic epidermal nevus and inflammatory linear verrucous epidermal nevus have in common well-circumscribed loci of parakeratosis beneath which the granular zone is absent, alternation of zones of ortho- and parakeratosis, and an epidermis tha…

Differential Diagnosis in Dermatopathology

Discussions

Pale-cell acanthoma and a plaque of psoriasis have numerous attributes histopathologic in common. Both are characterized by elongated epidermal rete ridges and correspondingly elongated dermal papillae. The long papillae house dilated, tortuous capi…