Histologic Diagnosis of Inflammatory Skin Diseases

Lichen sclerosus et atrophicus

Lichen sclerosus et atrophicus Synonyms Lichen sclerosis Lichen alba White spot disease Presentation stereotypical Age and sex Any age, but most common in middle-aged women Distribution of lesions Genitalia particularly, but also other sites such as…

Differential Diagnosis in Dermatopathology

Urticaria vs. Urticarial lesions of bullous pemphigoid

Papules, nodules, vesicles, and sometimes bullae that develop in response to “bites” of arthropods, among the most common offenders being mosquitoes, bedbugs, and mites of scabies….

Differential Diagnosis in Dermatopathology

Insect "bite" vs. Lymphomatoid papulosis

Papules, nodules, vesicles, and sometimes bullae that develop in response to “bites” of arthropods, among the most common offenders being mosquitoes, bedbugs, and mites of scabies….

Histologic Diagnosis of Inflammatory Skin Diseases

Eosinophilic folliculitis

Eosinophilic folliculitis Synonyms Sterile eosinophilic pustulosis Eosinophilic pustular dermatosis Circinate eosinophilic dermatosis Presentation stereotypical Age and sex Infants of both sexes, restricted usually to the scalp; young adults, especi…

Differential Diagnosis in Dermatopathology

Discussions

Psoriasis on volar skin and dyshidrotic dermatitis—the latter a disease that virtually always is restricted to volar skin or skin immediately adjacent to it—often share findings histopathologic: scale-crusts, psoriasiform acanthosis, foc…

Differential Diagnosis in Dermatopathology

Discussions

Urticaria and the urticarial stage of bullous pemphigoid have several findings histopathologic in common, chiefly superficial and mid- or deep dermal perivascular and interstitial mixed-cell infiltrates in which eosinophils are prominent in the inte…

Differential Diagnosis in Dermatopathology

Discussions

Although Mucha-Habermann disease (pityriasis lichenoides et varioliformis acuta) poses the greatest difficulty in differentiation clinically, and sometimes histopathologically, from lymphomatoid papulosis, a reaction to an insect “bite”…