Histologic Diagnosis of Inflammatory Skin Diseases

Lichen sclerosus et atrophicus

…tus associated with it, may be obscured partially by signs of excoriation and/or persistent rubbing. Vesicular and bullous lesions, some of them purpuric, develop on the genitalia of women especially. Squamous-cell carcinoma may arise in longstanding…

Differential Diagnosis in Dermatopathology

Urticaria vs. Urticarial lesions of bullous pemphigoid

Papules, nodules, vesicles, and sometimes bullae that develop in response to “bites” of arthropods, among the most common offenders being mosquitoes, bedbugs, and mites of scabies….

Differential Diagnosis in Dermatopathology

Insect "bite" vs. Lymphomatoid papulosis

Papules, nodules, vesicles, and sometimes bullae that develop in response to “bites” of arthropods, among the most common offenders being mosquitoes, bedbugs, and mites of scabies….

Histologic Diagnosis of Inflammatory Skin Diseases

Eosinophilic folliculitis

…mon: Pruritic papules, some eroded and ulcerated secondary to excoriation. Features differentiating: Pruritic papular eruption of HIV differs clinically from insect “bites” by predilection for the upper part of the trunk, neck, and arms a…

Differential Diagnosis in Dermatopathology

Discussions

…ranged in periodic fashion, and unless there are evidences of excoriation, they do not contain neutrophils; lymphocytes, rather than neutrophils, are present in scale-crusts; spongiotic vesicles are devoid of neutrophils; rete ridges vary in length;…

Differential Diagnosis in Dermatopathology

Discussions

…s of bullous pemphigoid often are accompanied by evidences of excoriation, such as linear erosions and hemorrhagic crusts. Urticarial lesions of bullous pemphigoid often assume arcuate, annular, polycyclic, serpiginous, and other outlines figurate th…

Differential Diagnosis in Dermatopathology

Discussions

…by a crust. Because the lesions are so pruritic, evidences of excoriation in the form of erosions, ulcerations, and hemorrhagic crusts are expected. In contrast, papules of lymphomatoid papulosis are not urticarial; rarely do they vesiculate, but the…