Search Results for: fibrin

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Histologic Diagnosis of Inflammatory Skin Diseases

Arthropod assaults

…accompanied, episodically, by signs of vasculitis, usually in the form of thrombi in the lumen of venules, but sometimes of fibrin deposited in the wall of venules. Findings of small-vessel vasculitis are seen in less than 15% of all biopsy…

Histologic Diagnosis of Inflammatory Skin Diseases

Selection of the Site

…a sparse perivascular and interstitial infiltrate of neutrophils and some nuclear “dust” of neutrophils, but no fibrin in the wall of venules. Although those paltry findings, in themselves, may be sufficient to make a diagnosis of…

Histologic Diagnosis of Inflammatory Skin Diseases

Cells That Mediate Inflammation (Inflammatory Cells)

…of the body to external trauma. When, as a response to injury, activation of the coagulation cascade results in formation of fibrin, which then casts a net at the surface of a wound, platelets attach to that network, thereby contributing to closure…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…iad bacteria of Bartonella species. 10.7.4A: Nodular dermatitis + 10.7.4B: Lymphocytes, plasma cells, histiocytes, necrosis, fibrin, fragments of necrotic inflammatory cells and pseudocarcinomatous (infundibular) proliferation + 10.7.4C + 10.7.4D =…

Histologic Diagnosis of Inflammatory Skin Diseases

Necrobiosis lipoidica

…four diseases. In the center of a palisade of histiocytes of granuloma annulare are found degeneration of collagen, a tad of fibrin, and abundant mucin; in that of necrobiosis lipoidica, abundant degenerated collagen in early lesions and crowded…

Histologic Diagnosis of Inflammatory Skin Diseases

Granuloma faciale

…clastic vasculitis, namely, neutrophils and nuclear “dust” of neutrophils in conjunction with venules that house fibrin in their wall. The sequence in which inflammatory cells enter lesions of erythema elevatum diutinum and granuloma…

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema elevatum diutinum

…lymphocytes, and plasma cells in zones of fibroplasia Prominent vasculature in the lesion; venules with a thick wall, but no fibrin in it Differential diagnosis histopathologic Granuloma faciale is identical with erythema elevatum diutinum….

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…les have been compromised by the infectious process. 10.47.13A: Vesicular dermatitis, intraepidermal, ballooned + 10.47.13B: Fibrin in a venule and a mixed-cell infiltrate rich in neutrophils = Infection by herpesvirus, fully developed The dense…

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