1 3 4 5 6 7 10
Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.20.1A: Nodular dermatitis, granulomatous + 10.20.1B: Numerous extravasated erythrocytes, siderophages, and fibrocytes = Dermatofibroma An important finding for diagnosis of a dermatofibroma such as this one is seen at the periph…

Differential Diagnosis in Dermatopathology

Discussions

Keloids and hypertrophic scars have many findings histopathologic in common (e.g., fibroplasia, telangiectases, infiltrates of inflammatory cells, mucin) and, in some instances, attributes of what seem to be both keloid and hypertrophic scar may be…

Differential Diagnosis in Dermatopathology

Keloid vs. Hypertrophic scar

A red, often ulcerated, boggy papule that represents a hyperplasia of small cutaneous vessels which are "fed" by an arteriole in the subcutaneous fat, the lesion resulting consistently from external trauma, usually in the form of a punctur…

Histologic Diagnosis of Inflammatory Skin Diseases

Cicatricial pemphigoid

Cicatricial pemphigoid Synonyms Benign mucosal pemphigoid Ocular pemphigus Desquamative gingivitis Essential shrinkage of the conjunctiva Benign mucous membrane pemphigoid Scarring pemphigoid Presentation stereotypical Age and sex Seventh decade mos…

Differential Diagnosis in Dermatopathology

Angiolymphoid hyperplasia with eosinophilia vs. Kimura’s disease

A red, often ulcerated, boggy papule that represents a hyperplasia of small cutaneous vessels which are "fed" by an arteriole in the subcutaneous fat, the lesion resulting consistently from external trauma, usually in the form of a punctur…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Atrophic lichen planus Atrophic discoid lupus erythematosus 1. Epidermis thinned, but not to near paper thin 1. Epidermis sometimes paper-thin 2. Wedge-shaped hypergranulosis in foci in repeatable fashion 2. No wedge-shaped hypergranulosis as…

Differential Diagnosis in Dermatopathology

Discussions

For many years, authors of publications in English used the terms “Kimura’s disease” and “angiolymphoid hyperplasia with eosinophilia” as synonyms. In truth, these two diseases are different in nearly every respect and…

Histologic Diagnosis of Inflammatory Skin Diseases

Lupus vulgaris

Lupus vulgaris Findings histopathologic Fully developed Collections of epithelioid histiocytes in the upper half of the dermis, some impinging on the epidermis, which is thinned Dense infiltrates of lymphocytes surrounding granulomas Fibrosis and t…

Histologic Diagnosis of Inflammatory Skin Diseases

Scrofuloderma

Scrofuloderma Findings histopathologic Fully developed Tuberculoid granulomas, many with extensive caseous necrosis in their center, present throughout the entire dermis and far into the subcutis Abscesses in some granulomas Fibroplasia in the uppe…

1 3 4 5 6 7 10