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Histologic Diagnosis of Inflammatory Skin Diseases

Traction alopecia

…of a follicle, rather than along the infundibulum mostly, the fibroplasia around infundibula and follicles is joined by lymphocytes, rather than lymphocytes in a band being separated from those epithelia by a zone of fibroplasia, and fibrous tracks…

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema elevatum diutinum

…lear “dust” of neutrophils throughout the zones of fibroplasia Scattered eosinophils, lymphocytes, and plasma cells in zones of fibroplasia Prominent vasculature in the lesion; venules with a thick wall, but no fibrin in it Differential…

Differential Diagnosis in Dermatopathology

Discussions

Keloids and hypertrophic scars have many findings histopathologic in common (e.g., fibroplasia, telangiectases, infiltrates of inflammatory cells, mucin) and, in some instances, attributes of what seem to be both keloid and hypertrophic scar may be…

Histologic Diagnosis of Inflammatory Skin Diseases

Cicatricial pemphigoid

Cicatricial pemphigoid Synonyms Benign mucosal pemphigoid Ocular pemphigus Desquamative gingivitis Essential shrinkage of the conjunctiva Benign mucous membrane pemphigoid Scarring pemphigoid Presentation stereotypical Age and sex Seventh decade mos…

Differential Diagnosis in Dermatopathology

Keloid vs. Hypertrophic scar

A red, often ulcerated, boggy papule that represents a hyperplasia of small cutaneous vessels which are “fed” by an arteriole in the subcutaneous fat, the lesion resulting consistently from external trauma, usually in the form of a punct…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Atrophic lichen planus Atrophic discoid lupus erythematosus 1. Epidermis thinned, but not to near paper thin 1. Epidermis sometimes paper-thin 2. Wedge-shaped hypergranulosis in foci in repeatable fashion 2. No wedge-shaped hypergranulosis as…

Differential Diagnosis in Dermatopathology

Angiolymphoid hyperplasia with eosinophilia vs. Kimura’s disease

A red, often ulcerated, boggy papule that represents a hyperplasia of small cutaneous vessels which are “fed” by an arteriole in the subcutaneous fat, the lesion resulting consistently from external trauma, usually in the form of a punct…

Differential Diagnosis in Dermatopathology

Discussions

For many years, authors of publications in English used the terms “Kimura’s disease” and “angiolymphoid hyperplasia with eosinophilia” as synonyms. In truth, these two diseases are different in nearly every respect and…

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