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Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Subcutaneous Fat: Panniculitis

…s fully developed lesion of erythema nodosum. The well-formed granulomas in lobules are reminiscent of those of subcutaneous sarcoidosis, but the widened fibrotic septa allow erythema nodosum to be identified for what it is. Figure 5.389 A&B….

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…suppurative infundibulitides, such as Majocchi’s “granuloma”; and (3) vesicants such as the oil, cantharidin, on surface epidermal keratocytes. Whenever neutrophils enter the epidermis in large numbers, the effects of enzymes releas…

Histologic Diagnosis of Inflammatory Skin Diseases

Study By Disease

…the scalp (Quiz #279) Eruptive capillary hemangioma (pyogenic granuloma) (Quiz #887) Erysipelas (Quiz #38) Erysipelas (Quiz #251) Erythema annular centrifugum (Quiz #505) Erythema annulare centrifugum (Quiz #56) Erythema annulare centrifugum (Quiz #2…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Perforating Diseases?

…in the basic pathologic mechanism. These include perforating granuloma annulare, perforating folliculitis, elastosis perforans serpiginosa and reactive perforating collagenosis.” Mehregan A. Perforating dermatoses: a clinicopathologic review….

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Necrobiosis?

…agen. …The necrobiotic area contains prominent mucin in granuloma annulare, fibrin in rheumatoid nodule, and degenerated collagen in necrobiosis lipoidica.” Warschaw KE, Cotton JP. Glossary. In: Farmer ER, Hood AF, eds. Pathology of the…

Histologic Diagnosis of Inflammatory Skin Diseases

Interstitial granulomatous dermatitis with arthritis

Interstitial granulomatous dermatitis with arthritis Synonyms Interstitial granulomatous dermatitis with cutaneous cords and arthritis Rheumatoid papules Palisaded and neutrophilic granulomatous dermatitis Presentation stereotypical Age and sex Ad…

Differential Diagnosis in Dermatopathology

Discussions

Interstitial granulomatous dermatitis with arthritis, a distinctive disease that appears usually in patients with rheumatoid-like arthritis, has many attributes in common with the mostly interstitial type of granuloma annulare. Lesions of both condi…

Differential Diagnosis in Dermatopathology

Discussions

The interstitial expression of granuloma annulare and of papular mucinosis have several findings histopathologic in common, among them mesenchymal cells with abundant pink cytoplasm scattered among bundles of collagen, multinucleate cells in section…

Differential Diagnosis in Dermatopathology

Discussions

Lesions of granuloma annulare that involve the subcutaneous fat mostly have many findings in common with rheumatoid nodule. Both diseases are associated with epithelioid histiocytes arrayed in a palisade around zones of degenerated collagen, mucin,…

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