Differential Diagnosis in Dermatopathology

Syringocystadenoma papilliferum vs. Hidradenoma papilliferum

A malignant neoplasm of melanocytes that, in the skin, begins as a macule and may become a patch or a papule. A flat lesion of melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly…

Differential Diagnosis in Dermatopathology

Discussions

…ngle specimen. The large nodular type is seen commonly in the hamartoma, nevus sebaceus. Often, the large nodules are pigmented heavily by melanin as a consequence of the activity of dendritic melanocytes housed within aggregations of neoplastic tric…

Differential Diagnosis in Dermatopathology

Discussions

…d malignant neoplasms that may arise within nevus sebaceus, a hamartoma marked by alterations of the dermis, the epidermis, and the epithelial structures of adnexa, as well at times of the subcutaneous fat. Clinically, it is relatively easy to suspec…

Differential Diagnosis in Dermatopathology

Discussions

…is an inflammatory process, whereas a collagenous nevus is a hamartoma. A residuum of a once dense infiltrate of lymphocytes and plasma cells may be present even at a late stage of morphea. No inflammatory cells are seen, however, in a collagenous n…

Differential Diagnosis in Dermatopathology

Discussions

…r lichen planus, and lichen striatus. An epidermal nevus is a hamartoma that, on biopsy, is found to have different characteristics histopathologic that are reflected in differences clinical. Among the findings histopathologic in epidermal nevi are v…

Differential Diagnosis in Dermatopathology

Morphea, late stage vs. Collagenous nevus

A malignant neoplasm of melanocytes that, in the skin, begins as a macule and may become a patch or a papule. A flat lesion of melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly…