Differential Diagnosis in Dermatopathology

Discussions

…ng atypia. Connective tissue nevi of the skin, in general, are hamartomas that consist of alterations of one or more components of the extracellular matrix: collagen, elastin, and glycosaminoglycan (proteoglycans). Collagenomas are hamartomas of coll…

Differential Diagnosis in Dermatopathology

Discussions

Porokeratotic epidermal nevus and inflammatory linear verrucous epidermal nevus have in common well-circumscribed loci of parakeratosis beneath which the granular zone is absent, alternation of zones of ortho- and parakeratosis, and an epidermis tha…

Differential Diagnosis in Dermatopathology

Morphea, late stage vs. Collagenous nevus

A malignant neoplasm of melanocytes that, in the skin, begins as a macule and may become a patch or a papule. A flat lesion of melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly…

Histologic Diagnosis of Inflammatory Skin Diseases

Leukocytoclastic vasculitis

Leukocytoclastic vasculitis Synonyms Leukocytoclastic angiitis Allergic vasculitis Hypersensitivity angiitis Hypersensitivity vasculitis Anaphylactoid purpura Immune complex vasculitis Purpura rheumatica Presentation stereotypical Age and sex Any ag…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen striatus

Lichen striatus Synonyms Linear lichenoid dermatosis Presentation stereotypical Age and sex Mostly girls, but sometimes boys and young adults of both sexes Distribution of lesions Usually an extremity Arrangement of lesions Linear Individual lesions…