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Histologic Diagnosis of Inflammatory Skin Diseases

Reticulohistiocytic granuloma

…ed with arthritis. Findings histopathologic Fully developed Histiocytes, some slightly foamy, in dense diffuse array throughout much or all of the dermis and accompanied usually by a sprinkling of neutrophils, eosinophils, lymphocytes, and plasma c…

Differential Diagnosis in Dermatopathology

Discussions

…stitially in foci in the reticular dermis; some multinucleate histiocytes (histiocytic giant cells) are present episodically in the infiltrate; and elastophagocytosis by histiocytes is notable sometimes. When histiocytes are disposed in interstitial…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Histiocytoses?

…plasm that does not house foreign material, i.e., epithelioid histiocytes, and for the other those whose cytoplasm harbors foreign material, e.g., lipophages, siderophages, and melanophages. The term histiocytoma is confusing because it implies that…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…rstitla dermatitis, and panniculitis, lobular + 10.68.1B: Histiocytes, many of them multinucleate, in palisaded array around foci of extensive degeneration of collagen and extracellular deposits of lipid = Necrobiotic xanthogranuloma ¬†Necrobiosis…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Langerhans’ Cell Granulomatosis?

…The cells of histiocytosis X [HX] have been designated “histiocytes” but the “ordinary” histiocytes encountered in healthy skin, in histiocytoma or various granulomatous processes are devoid of the granules. It could be inferr…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen nitidus

…e separated widely from one another and expanding them; a few histiocytes sometimes present in the center of collections of lymphocytes Fully developed Circumscribed collections of epithelioid histiocytes, some of them multinucleate, in discrete fo…

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