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Histologic Diagnosis of Inflammatory Skin Diseases

Reticulohistiocytic granuloma

…ing of neutrophils, eosinophils, lymphocytes, and plasma cells Histiocytes with distinctive amphophilic slightly granular cytoplasm; darker in the center than at the periphery Many binucleate and multinucleate histiocytes Some histiocytes with abnorm…

Differential Diagnosis in Dermatopathology

Discussions

…rstitially in foci in the reticular dermis; some multinucleate histiocytes (histiocytic giant cells) are present episodically in the infiltrate; and elastophagocytosis by histiocytes is notable sometimes. When histiocytes are disposed in interstitial…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Histiocytoses?

…cates that malignant fibrous histiocytoma is not a neoplasm of histiocytes, but of fibrocytes. Malignant histiocytosis is a misnomer. The condition is a lymphoma, the cells that constitute it being lymphocytes, not histiocytes. The designation &#8220…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ipoidica. 10.68.2A: Nodular and interstitial dermatitis, histiocytes predominate, and panniculitis, lobular + 10.68.2B: Numerous multinucleate histiocytes, many of them Touton type, and lymphoid follicles + 10.68.2C + 10.68.2D…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Langerhans’ Cell Granulomatosis?

…nated “histiocytes” but the “ordinary” histiocytes encountered in healthy skin, in histiocytoma or various granulomatous processes are devoid of the granules. It could be inferred that histiocytes produce the granules only in…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen nitidus

…ae separated widely from one another and expanding them; a few histiocytes sometimes present in the center of collections of lymphocytes Fully developed Circumscribed collections of epithelioid histiocytes, some of them multinucleate, in discrete f…

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