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A Clinical Atlas of 101 Common Skin Diseases

Lichen Planus

An inflammatory process consisting usually of violaceous papules that have a polygonal outline and flat top, and that tends to favor flexural surfaces of skin and the buccal mucosa of the oral cavity. It sometimes affects follicles and nail units as…

A Clinical Atlas of 101 Common Skin Diseases

Dyshidrotic Dermatitis

A pruritic papular and vesicular inflammatory process of unknown cause that tends to affect the sides of fingers and toes, as well as palms and soles. The name “dyshidrotic” is misleading; the condition has no relation whatever to eccrin…

A Clinical Atlas of 101 Common Skin Diseases

Candidiasis

An inflammatory disease caused by the yeast Candida albicans and manifested clinically as erythematous papules and pustules that may become confluent to form plaques in the case of the former and erosions in the case of the latter. The nail unit may…

A Clinical Atlas of 101 Common Skin Diseases

Melanocytic Nevi and Melanotic Macules

Hamartomas (“congenital” melanocytic nevi) and benign neoplasms (“acquired” melanocytic nevi) of various specific types, all of which are composed of abnormal melanocytes and manifested clinically as lesions of different colo…

A Clinical Atlas of 101 Common Skin Diseases

Basal-Cell Carcinoma

A malignant neoplasm made up of abnormal germinative cells analogous to those that compose the folliculosebaceous-apocrine germ in an embryo and that usually manifests clinically as a papule or nodule which may become ulcerated. On the basis of clin…

Histologic Diagnosis of Inflammatory Skin Diseases

Embryologic Development

…ructures, i.e., epidermis (surface and infundibular), apocrine units, sebaceous units, hair follicles, eccrine units, and nail units, come from ectoderm. Melanocytes, nerves, and specialized sensory receptors develop from neuroectoderm. The other ele…

Histologic Diagnosis of Inflammatory Skin Diseases

Hair Follicles

…re 1.37 Very early anagen. At the base of the isthmus is a new follicular germ and beneath it sits an incipient follicular papilla. The germ-like structure, like the germ of the infundibuloapocrine-sebaceous- follicular unit in an embryo, is characte…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Dermal Papilla?

…nd of catagen, and are “awakened” by a call from a follicular papilla newly formed into a unit cohesive immediately beneath them. That phenomenon recapitulates events that transpired in the embryo when surface ectoderm generated a follicu…

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