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Histologic Diagnosis of Inflammatory Skin Diseases

Arthropod assaults

Arthropod assaults Synonyms Insect “bite” Bug bite Insect bite reaction Papular urticaria Lichen urticatus Strophulus Presentation stereotypical Age and sex Any age and both sexes Distribution of lesions At times only a single lesion a…

Histologic Diagnosis of Inflammatory Skin Diseases

Infundibulofolliculitis, disseminate and recurrent

Infundibulofolliculitis, disseminate and recurrent Presentation stereotypical Age and sex Young Africans and African-Americans, especially men Distribution of lesions Widespread Arrangement of lesions Scattered and discrete; equidistant from one ano…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Perforating Diseases?

“Perforating dermatoses: . . . various cutaneous disorders are discussed in which the process of perforation and elimination of various tissue components plays a major role in the basic pathologic mechanism. These include perforating granulom…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Tricho-, pilo-, folliculo- ?

“pilo- [L. pilus]. Combining form indicating hair. . . . tricho- [Gr. thrix, trichas, hair]. A prefix denoting a relationship to hair. . . . follicle- [L. folliculus, little bag]. A small secretory sac or cavity.” Tabers Cyclopedic Me…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…8221; of nuclear chromatin and multinucleate corneocytes in an infundibulum = Infection by herpesvirus, early If a microscopist fails to take note of the subtle changes in the infundibulum shown here, the diagnosis of herpesvirus will be missed. Not…

Histologic Diagnosis of Inflammatory Skin Diseases

Acne vulgaris

Synonyms Acne simplex Presentation stereotypical Age and sex Adolescents of both sexes; usually more severe in males. May affect neonates. Distribution of lesions Regions in which large sebaceous units are joined to vellus follicles, i.e., the face,…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Common Baldness—an Inflammatory Disease?

“The results also show that inflammation in MPA [male pattern alopecia] is a relatively consistent finding and that, although often insignificant, this frequently leads to an inflammatory folliculitis, perifollicular fibrosis, and unusually…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.94.1A: Infundibulitis, spongiotic, and peri-infundibulitis, granulomatous + 10.94.1B: Lymphocytes and plasma cells around collections of epithelioid histiocytes = Rosacea, papular ┬áSpongiosis in an infundibulum is a finding comm…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Epidermal Cyst and Epidermoid Cyst?

“Epidermoid cyst. Synonym: Sebaceous cyst, steatoma, epithelial cyst. Definition: A cyst containing keratin and its breakdown products, surrounded by an epidermoid wall.” Mackie RM. Epidermal skin tumors. In: Champion RH, Burton JL, Eb…

Histologic Diagnosis of Inflammatory Skin Diseases

Our Definition of “Inflammation” and “Inflammatory Disease”

What follow now are our definitions of the terms inflammation and inflammatory disease as we employ them in this volume. Inflammation. Changes in tissue that occur typically as a reaction to injury of any kind (e.g., mechanical, actinic, chemical,…

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