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Histologic Diagnosis of Inflammatory Skin Diseases

Images

…221; of nuclear chromatin and multinucleate corneocytes in an infundibulum = Infection by herpesvirus, early If a microscopist fails to take note of the subtle changes in the infundibulum shown here, the diagnosis of herpesvirus will be missed. Not u…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Common Baldness—an Inflammatory Disease?

…erate inflammatory infiltrate at the level of the isthmus and infundibulum. This can also be seen in scalp biopsies from normal patients or those with seborrheic dermatitis. We could not detect obvious inflammation in the lower portion of deeply seat…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…ug of Corneocytes Cast of cornified cells in a dilated infundibulum. Click image to enlarge. + Thickened epidermal basement membrane = Discoid lupus erythematosus + Spongiosis in affected infundibula, plugs of both ortho- and parakeratotic c…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Epidermal Cyst and Epidermoid Cyst?

…being an infundibular cyst, a true epidermal cyst because the infundibulum is as much epidermis as is surface epidermis. The epithelium that lines virtually all other cutaneous cysts is like that of adnexal epithelium, namely, follicular, sebaceous,…

Histologic Diagnosis of Inflammatory Skin Diseases

Arthropod assaults

…ot uncommonly, the actual site of the bite is an ostium of an infundibulum, that structure containing delicacies loved by insects, among them being bacteria, yeasts, mites, and lipids from sebaceous glands, the latter emitting an odor (by virtue of e…

Histologic Diagnosis of Inflammatory Skin Diseases

Eccrine Units

…relation to the hair follicle per se, which resides below the infundibulum, although in continuity with it. The hair itself does pass through the infundibular canal en route to reaching the surface of the skin, from which it exits by way of an ostium…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…epithelioid histiocytes = Rosacea, papular ┬áSpongiosis in an infundibulum is a finding common in rosacea and in analogues of it, to wit, perioral and periocular dermatitis. 10.94.2A: Peri-infundibulitis, suppurative granulomatous + 10.94.2…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Tricho-, pilo-, folliculo- ?

…; later the same process is called trichodiscoma. Although an infundibulum of epidermis is positioned in the center of each segment of fibrofolliculoma, the condition actually is an abnormality of mantles of a follicle, those distinctive cords of und…

Histologic Diagnosis of Inflammatory Skin Diseases

Traction alopecia

…dlike infiltrate of lymphocytes may extend from the top of an infundibulum to the base of a follicle, rather than along the infundibulum mostly, the fibroplasia around infundibula and follicles is joined by lymphocytes, rather than lymphocytes in a b…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…1.2B: Collections of neutrophils around a hair in a distorted infundibulum, histiocytes mostly in the vicinity immediate of the altered infundibulum, dense lymphoplasmacytic infiltrates, and fibroplasia = Acne keloidalis Changes identical with th…

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