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Resolving Quandaries in Dermatology, Pathology & Dermatopathology


…lesions is the presence of cytologic atypia, or dysplasia, of melanocytes.” (Greene et al. Lancet 1980). In 1981 they stated that “dysplasia is used as a synonym for melanocytic atypia rather than for hyperplasia of atypical melanocytes.&…

Dermatology Practical & Conceptual

Strategies for early recognition of cutaneous melanoma-present and future

…neous melanoma is a highly aggressive malignant tumor of skin melanocytes with an increasing incidence in most countries of the world, especially in the fair-skinned populations. Despite all preventive and therapeutic efforts, malignant melanoma is s…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…ndulate between rete ridges and dermal papillae 5. Nests of melanocytes predominate over melanocytes disposed as solitary units 5. Abnormal melanocytes arrayed mainly as solitary units in at least some high-power fields 6. Nests of melanocytes re…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…m in types of cells other than keratocytes, such as ballooned melanocytes of nevi and melanomas (balloon-cell nevi and balloon cell melanoma, respectively). Figure 3.6 Ballooning (intracellular edema), reticular alteration, and vesiculation. BASAL…

Dermatology Practical & Conceptual

Melanoma arising in a giant nevus spilus maculosus

…on of basal keratinocytes but no substantial proliferation of melanocytes (Figure 5). Histopathology of the nodule showed a nodular melanoma with an invasion thickness of 4.5 mm (Figure 6). On the basis of the clinical and pathologic findings we made…

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