Search Results for: morphea

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Histologic Diagnosis of Inflammatory Skin Diseases

Limitations of the Algorithmic Method

…hat encircle those of the deep plexus, if that latter plexus is involved at all. Notable exceptions to that general rule are morphea (see Fig. 5.32), necrobiosis lipoidica, and interstitial granulomatous dermatitis with arthritis, many examples of…

Histologic Diagnosis of Inflammatory Skin Diseases

Mycosis fungoides

…is. Last, some lymphocytes in mycosis fungoides, unlike the situation in granuloma annulare, may have a cerebriform outline. Morphea differs from interstitial mycosis fungicides by the infiltrate tending to be “bottom heavy” and…

Histologic Diagnosis of Inflammatory Skin Diseases

Graft-versus-host disease/Eruption of lymphocyte recovery

…eplaced by fibroplasia. The changes sclerodermatous in chronic graft-versus-host disease are indistinguishable from those of morphea as it is encountered in circumstances as dissimilar as in Shulman’s syndrome and porphyria cutanea tarda….

Differential Diagnosis in Dermatopathology

Interstitial granuloma annulare vs. Interstitial mycosis fungoides

The term, dermatofibrosarcoma protuberans (DFSP), was coined by Hoffman in 1925 to signify a protuberant, often multinodular cutaneous tumor that showed progressive growth. Darier and Ferrand had described a case of the disease a year before, and…

Differential Diagnosis in Dermatopathology

Discussions

…e associated with lymphocytes in the interstitium or if there is a hint of crowding of bundles of collagen, the diagnosis is morphea. At times the interstitial infiltrates of the two very different diseases, mycosis fungoides and morphea, are very…

Dermatoscopic findings of atrophic dermatofibrosarcoma protuberans

Dermatoscopic findings of atrophic dermatofibrosarcoma protuberans

…tumor that is called atrophic DFSP. It occurs as an atrophic, asymptomatic plaque that can be difficult to distinguish from morphea, morphea like basal cell carcinoma, scar, lipoatrophy and atrophic dermatofibroma [3]. Although the clinical…

Histologic Diagnosis of Inflammatory Skin Diseases

Acrodermatitis chronica atrophicans

…as the “idiopathic atrophoderma Pasini and Pierini.” Lichen sclerosus et atrophicus, a superficial expression of morphea, consists of lesions that usually are smaller, more localized, and more ivory colored than those of acrodermatitis…

Histologic Diagnosis of Inflammatory Skin Diseases

Degos’ disease (malignant atrophic papulosis)

…ierini, an end stage of morphea, tends to be hyperpigmented. Lichen sclerosus et atrophicans, a superficial manifestation of morphea, may present itself as small white macules, but those tend to be joined by a violaceous rim that is unaffiliated…

Histologic Diagnosis of Inflammatory Skin Diseases

Lipodystrophy

…ulin resistant) hyperlipoproteinemia, kidney disease, mental retardation, and schizophrenia. Differential diagnosis clinical Morphea usually is asymmetrical in distribution of lesions and presents itself as discrete indurated plaques. Linear…

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