Search Results for: morphea

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Histologic Diagnosis of Inflammatory Skin Diseases

Necrobiosis lipoidica

…which occurs in discrete loci that become surrounded by histiocytes aligned in a palisade. In both necrobiosis lipoidica and morphea, the lower two thirds of the reticular dermis often is involved preferentially. In time, the changes in collagen in…

Histologic Diagnosis of Inflammatory Skin Diseases

Limitations of the Algorithmic Method

…hat encircle those of the deep plexus, if that latter plexus is involved at all. Notable exceptions to that general rule are morphea (see Fig. 5.32), necrobiosis lipoidica, and interstitial granulomatous dermatitis with arthritis, many examples of…

Histologic Diagnosis of Inflammatory Skin Diseases

Degos’ disease (malignant atrophic papulosis)

…ierini, an end stage of morphea, tends to be hyperpigmented. Lichen sclerosus et atrophicans, a superficial manifestation of morphea, may present itself as small white macules, but those tend to be joined by a violaceous rim that is unaffiliated…

Differential Diagnosis in Dermatopathology

Interstitial granuloma annulare vs. Interstitial mycosis fungoides

A malignant neoplasm made up of abnormal germinative cells analogous to those that compose the folliculosebaceous-apocrine germ in an embryo and that usually manifests clinically as a papule or nodule which may become ulcerated. On the basis of…

Differential Diagnosis in Dermatopathology

Discussions

…e associated with lymphocytes in the interstitium or if there is a hint of crowding of bundles of collagen, the diagnosis is morphea. At times the interstitial infiltrates of the two very different diseases, mycosis fungoides and morphea, are very…

Dermatoscopic findings of atrophic dermatofibrosarcoma protuberans

Dermatoscopic findings of atrophic dermatofibrosarcoma protuberans

…tumor that is called atrophic DFSP. It occurs as an atrophic, asymptomatic plaque that can be difficult to distinguish from morphea, morphea like basal cell carcinoma, scar, lipoatrophy and atrophic dermatofibroma [3]. Although the clinical…

Histologic Diagnosis of Inflammatory Skin Diseases

Acrodermatitis chronica atrophicans

…as the “idiopathic atrophoderma Pasini and Pierini.” Lichen sclerosus et atrophicus, a superficial expression of morphea, consists of lesions that usually are smaller, more localized, and more ivory colored than those of acrodermatitis…

Histologic Diagnosis of Inflammatory Skin Diseases

The Algorithmic Method

…e nodular/tumor stage of that lymphoma. Lymphocytes, plasma cells, and eosinophils are present together in an early stage of morphea (see Fig. 5.32), and histiocytes, lymphocytes, eosinophils, and neutrophils occur together in interstitial…

Histologic Diagnosis of Inflammatory Skin Diseases

Lipodystrophy

…ulin resistant) hyperlipoproteinemia, kidney disease, mental retardation, and schizophrenia. Differential diagnosis clinical Morphea usually is asymmetrical in distribution of lesions and presents itself as discrete indurated plaques. Linear…

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