Search Results for: morphea

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Differential Diagnosis in Dermatopathology

Interstitial granuloma annulare vs. Interstitial mycosis fungoides

A malignant neoplasm made up of abnormal germinative cells analogous to those that compose the folliculosebaceous-apocrine germ in an embryo and that usually manifests clinically as a papule or nodule which may become ulcerated. On the basis of clin…

Dermatology Practical & Conceptual

Dermatoscopic findings of atrophic dermatofibrosarcoma protuberans

…B). A skin biopsy was taken with the preliminary diagnosis of morphea and cutaneous mastocytosis. Histopathological examination of H&E (hematoxylin and eosin) stained sections revealed epidermal atrophy, increase in melanin in basal keratinocytes…

Histologic Diagnosis of Inflammatory Skin Diseases

Acrodermatitis chronica atrophicans

…al of atrophy, except for “burned out” patches of morphea known as the “idiopathic atrophoderma Pasini and Pierini.” Lichen sclerosus et atrophicus, a superficial expression of morphea, consists of lesions that usually are sma…

Histologic Diagnosis of Inflammatory Skin Diseases

Degos’ disease (malignant atrophic papulosis)

…pattern. Atrophoderma of Pasini and Pierini, an end stage of morphea, tends to be hyperpigmented. Lichen sclerosus et atrophicans, a superficial manifestation of morphea, may present itself as small white macules, but those tend to be joined by a vi…

Differential Diagnosis in Dermatopathology

Discussions

…oides. Another simulator of interstitial mycosis fungoides is morphea, which should not be confused for interstitial granuloma annulare because no histiocytes are accompanying. If any lymphocytes are present in the epidermis or have nuclei with a dec…

Differential Diagnosis in Dermatopathology

Keloid vs. Hypertrophic scar

A malignant neoplasm made up of abnormal germinative cells analogous to those that compose the folliculosebaceous-apocrine germ in an embryo and that usually manifests clinically as a papule or nodule which may become ulcerated. On the basis of clin…

Histologic Diagnosis of Inflammatory Skin Diseases

Lipodystrophy

…tardation, and schizophrenia. Differential diagnosis clinical Morphea usually is asymmetrical in distribution of lesions and presents itself as discrete indurated plaques. Linear scleroderma on the forehead and scalp (en coup de sabre) is unilateral…

Histologic Diagnosis of Inflammatory Skin Diseases

Cells That Mediate Inflammation (Inflammatory Cells)

…diagnosis is likely to be mycosis fungoides and if not that, morphea. Lymphocytes are motile, but they move much less adroitly than do neutrophils. For that reason, they are seen in sections of tissue to surround venules, in contrast to neutrophils…

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