Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Apoptosis?

…ven names such as Civatte bodies, colloid bodies, single-cell necrobiosis, sunburn cells, and dyskeratotic cells without their basic nature having been recognized… Weedon D, Searle J, Kerr JF. Apoptosis: its nature and implications for dermato…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Perivascular Dermatitis

…t phenomenon being witnessed in morphea, lupus profundus, and necrobiosis lipoidica. A dramatic presentation of a “bottom heavy” infiltrate of lymphocytes occurs in alopecia areata in which follicles are all in late catagen (Fig. 5.153 A-…

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema nodosum

…mptoms of inflammatory or neoplastic disease of the pancreas. Necrobiosis lipoidica consists of erythematous plaques with a yellow hue that tend to ulcerate and that are not painful. Findings histopathologic Early Fibrous septa in the subcutaneous…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Pseudopelade?

…es with specificity. Chief among those are eczema, dysplasia, necrobiosis, parapsoriasis, and pseudopelade. None of those words is necessary because none has specificity. If the aim of diagnosis is to identify diseases for what they are precisely and…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Vasculitis

…septa in the subcutaneous fat) of a still-evolving lesion of necrobiosis lipoidica, of Wegener’s granulomatosis, and of Crohn’s disease. Figure 5.219 A&B. “Lymphocytic vasculitis”: an epiphenomenon. So-called lymphocyt…

Histologic Diagnosis of Inflammatory Skin Diseases

Introduction

…ery incipient stage of those diseases, and for distinguishing necrobiosis lipoidica from morphea at a very late “burned out” stage. The terms “anetoderma,” “poikiloderma,” and “lipodystrophy,” unmodifie…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Necrotizing Vasculitis?

…gmented epithelioid melanocytomas,” dyshidrosis,” necrobiosis,” eczema,” etc., etc., etc. “The necrotizing vasculitides include a variety of clinical disorders associated with segmental inflammation and necrosis of the…