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Histologic Diagnosis of Inflammatory Skin Diseases

Dermatofibroma

…l, targetoid Individual lesions A papule usually, a plaque or nodule uncommonly, and a tumor (giant dermatofibroma) rarely; tends to be reddish early, brown late; a papule or nodule early, a macule (sometimes depressed below the surface of the skin)…

Dermatology Practical & Conceptual

Yellow color upon dermatoscopy does not exclude melanoma!

…t because of the presence of a recently developed and growing nodule located on her left cheek. Clinically, the lesion appeared as a dome-shaped yellow to reddish nodule with well-defined borders that was surrounded by a collarette-like scale (Figure…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Churg-Strauss Granuloma and Allergic Granulomatosis?

…nt occurrence in this syndrome are cutaneous and subcutaneous nodules showing the typical connective tissue alteration. These are of significant value for diagnosis by biopsy.” Today, as in 1951, it is difficult for a reader with a critical tur…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Chondrodermatitis Nodularis Helicis?

…ear, and protrusions and depressions, as well as formation of nodules. It is very well possible, therefore, that cartilage thus changed has been damaged by some influence (of traumatic, chemical, or thermal nature). . . . Until the cause has been elu…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Pseudomalignancies?

…is a special lesion, a pseudocancer, occurring as an isolated nodule, usually on the face, and mimicking squamous cell carcinoma.” Wolff K, Johnson RA, Suurmond D. Fitzpatrick’s Color Atlas and Synopsis of Clinical Dermatology. 5th ed. N…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…red were referred to in times past as “pseudorheumatoid nodule.” In fact, they are those of granuloma annulare as evidenced by the abundant mucin in the center of some palisades of histiocytes. In short, there is rheumatoid nodule, but no…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…cum body-like inclusions = Farmer”s pox (Milker”s nodule/orf) + A few neutrophils sprinkled in the epidermis and a sparse perivascular infiltrate of lymphocytes mostly = Irritant contact dermatitis + Individual necrotic keratocytes an…

Histologic Diagnosis of Inflammatory Skin Diseases

Necrobiosis lipoidica

…l diagnosis clinical Erythema nodosum consists of tender red nodules and plaques that develop suddenly on the anterior surface of the legs and disappear in weeks without residua, save for hyperpigmentation. Hypodermitis sclerodermiformis tends to in…

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