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Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Halo Phenomenon?

…halo of depigmentation appears episodically around melanocytic nevi of different types, especially Clark’s nevus and small superficial congenital nevi, but that occurrence is different from, and unrelated to, regression of melanoma. The concept…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Nuclear Atypia, Cytoplasmic Atypia, and Architectural Atypia?

…s with nuclear atypia in atypical (dysplastic) nevomelanocytic nevi. Hum Pathol 1990;21:51-58. “In our view, both cytologic atypia and architectural atypia are necessary to enhance specificity of diagnosis [of dysplastic nevi].” “T…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

ABCDEs?

…, clinically and histopathologically, are acquired melanocytic nevi that can be classified and named eponymically for Unna, Miescher, Spitz, Clark, and Reed. Clark’s nevi, by far the most common melanocytic nevi in man, usually are tiny, about…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Changing Mole?

…y of those being superficial and “deep” congenital nevi, followed by superficial congenital nevi, and then by Clark’s nevi. Uncommonly, melanomas arise in conjunction with Unna’s and Miescher’s nevi, both of those being…

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