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Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Mycosis Fungoides—Increasing in Incidence?

…ral surfaces, and, in women, the breasts. Histopathologically, patches and subtle plaques are typified in the upper part of the dermis by patchy lichenoid infiltrates of lymphocytes associated with wiry bundles of collagen arrayed haphazardly and in…

Differential Diagnosis in Dermatopathology

Discussions

…oma. Melanoma in situ on sun-damaged skin of a face, like the patch stage of Kaposi’s sarcoma and the patch stage of mycosis fungoides (e.g., parapsoriasis en plaques), is not life-threatening. Only when papulation or nodularity supervenes (de…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Cutaneous T-cell Lymphoma?

…h a long evolution. Three kinds of lesions are characteristic: patches, plaques, and tumours. A patch is a flat skin lesion recognizable by the fact that its colour is different from that of the surrounding normal skin. In CTCL, patches are often ery…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.80.1A: Perivascular dermatitis, lymphocytic + 10.80.1B: Lymphocytes in tiny foci of spongiosis = Pityriasis alba ┬áThe changes could be misinterpreted as those of a flat lesion of mycosis fungoides, but the absence of any alterat…

Histologic Diagnosis of Inflammatory Skin Diseases

Our Definition of “Inflammation” and “Inflammatory Disease”

What follow now are our definitions of the terms inflammation and inflammatory disease as we employ them in this volume. Inflammation. Changes in tissue that occur typically as a reaction to injury of any kind (e.g., mechanical, actinic, chemical,…

Clinical Case Studies

Nevus of Ota

INITIAL PRESENTATION A 32-year-old Asian man presented with a long-standing patch of gray-brown discoloration under his left eye. (Figure 1) He noted an increasing prominence of the pigmentation over the preceding 15 years. The patient had a history…

Clinical Case Studies

Study By Disease

…by virtue of treatments various (Quiz #792) Mycosis fungoides, patch stage (Quiz #12) Mycosis fungoides, patch stage (Quiz #124) Mycosis fungoides, patch/plaque (Quiz #556) Mycosis fungoides, plaque (Quiz #557) Mycosis fungoides, plaque (Quiz #558) M…

Histologic Diagnosis of Inflammatory Skin Diseases

Pityriasis rosea

…e pattern” on the trunk Individual lesions “Herald patch” or “mother patch” refers to the appearance of the first lesion, i.e., an oval or round plaque with delicate collarettes of scale at its periphery. That lesion her…

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