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Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Primary and Secondary Lesions?

“Some of the appearances observed in cutaneous diseases are caused directly by the deposition of morbid products in the skin. These bear the name of Primary symptoms or eruptions, Efflorescentiae cutaneae primariae. But these eruptions often…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Mycosis Fungoides—Increasing in Incidence?

…ral surfaces, and, in women, the breasts. Histopathologically, patches and subtle plaques are typified in the upper part of the dermis by patchy lichenoid infiltrates of lymphocytes associated with wiry bundles of collagen arrayed haphazardly and in…

Differential Diagnosis in Dermatopathology

Discussions

…oma. Melanoma in situ on sun-damaged skin of a face, like the patch stage of Kaposi’s sarcoma and the patch stage of mycosis fungoides (e.g., parapsoriasis en plaques), is not life-threatening. Only when papulation or nodularity supervenes (de…

Clinical Case Studies

Nevus of Ota

INITIAL PRESENTATION A 32-year-old Asian man presented with a long-standing patch of gray-brown discoloration under his left eye. (Figure 1) He noted an increasing prominence of the pigmentation over the preceding 15 years. The patient had a history…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Radial Growth Phase versus Vertical Growth Phase of Melanoma?

“The essence of the radial growth phase is the incapacity to form tumor nodules in the dermis. Thus the radial growth phase may also be called nontumorigenic. . . . The vertical growth phase is, by definition, the appearance of a population o…

Differential Diagnosis in Dermatopathology

Study By Disease

…by virtue of treatments various (Quiz #792) Mycosis fungoides, patch stage (Quiz #12) Mycosis fungoides, patch stage (Quiz #124) Mycosis fungoides, patch/plaque (Quiz #556) Mycosis fungoides, plaque (Quiz #557) Mycosis fungoides, plaque (Quiz #558) M…

Histologic Diagnosis of Inflammatory Skin Diseases

Our Definition of “Inflammation” and “Inflammatory Disease”

What follow now are our definitions of the terms inflammation and inflammatory disease as we employ them in this volume. Inflammation. Changes in tissue that occur typically as a reaction to injury of any kind (e.g., mechanical, actinic, chemical,…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.80.1A: Perivascular dermatitis, lymphocytic + 10.80.1B: Lymphocytes in tiny foci of spongiosis = Pityriasis alba ┬áThe changes could be misinterpreted as those of a flat lesion of mycosis fungoides, but the absence of any alterat…

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