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Histologic Diagnosis of Inflammatory Skin Diseases

Lichen planus

…traction alopecia, which also presents itself as a lichenoid peri-infundibulitis and perifolliculitis of lymphocytes and ends with alopecia that is permanent. As a rule, the bandlike infiltrate of lymphocytes in traction alopecia does not descend mu…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…on alopecia is an inflammatory disease; it exhibits lichenoid peri-infundibulitis and perifolliculitis “early” in its course; trichotillomania, by contrast, is not an inflammatory disease. 10.108.2A: Section of a biopsy specimen fro…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…s involved usually in a 4 mm biopsy specimen 2. Suppurative infundibulitis prominent 2. Suppurative infundibulitis and granulomatous peri-infundibulitis prominent 3. Peri-infundibulitis not consequential 3. Peri-infundibulitis often predominant…

Histologic Diagnosis of Inflammatory Skin Diseases

"Perforating folliculitis" of chronic renal disease

…nal disease Comment This condition, essentially a suppurative infundibulitis, is vexing to patients practically and to physicians conceptually. It is troubling to patients because the suppurative infundibulitis induces maddening pruritus, and is frus…

Differential Diagnosis in Dermatopathology

Discussions

…itions turns on the fact that acne vulgaris essentially is an infundibulitis, and not a peri-infundibulitis, whereas rosacea is both an infundibulitis and a peri-infundibulitis. Granulomatous inflammation is basic to papules of rosacea, where it tend…

Differential Diagnosis in Dermatopathology

Study By Disease

…ption, papulosquamous (lamotrigin) (Quiz #592) Drug eruption, peri-infundibulitic (Quiz #203) Drug eruption, perivascular and interstitial (Quiz #215) Drug eruption, perivascular and interstitial (presumably) (Quiz #213) Drug eruption, pustular (Quiz…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Distinctive but Nonspecific Findings Using High Magnification

…tal finding, such as in response to the “bite” of an insect. PERI-INFUNDIBULAR AND PERIFOLLICULAR FIBROPLASIA Fibrosis around infundibula alone or infundibula and part of follicles together as occurs in any longstanding peri-infundibulitis mostly, e…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…n the dermis and/or dense, wedge-shaped, superficial and deep perivascular and interstitial infiltrate of lymphocytes, plasma cells, neutrophils, and eosinophils = Tick bite reaction + Keratocytes with steel-gray nuclei and “margination&#8221…

Histologic Diagnosis of Inflammatory Skin Diseases

Arthropod assaults

…y cells is a clue to an insect “bite.” Spongiotic infundibulitis in the center of a wedge-shaped, perivascular and interstitial infiltrate made up of lymphocytes mostly is a clue to an insect “bite.” A nodular infiltrate compo…

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