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Differential Diagnosis in Dermatopathology

Granular-cell tumor vs. Xanthoma

Hamartomas (“congenital” melanocytic nevi) and benign neoplasms (“acquired” melanocytic nevi) of various specific types, all of which are composed of abnormal melanocytes and manifested clinically as lesions of different colo…

Differential Diagnosis in Dermatopathology

Pale-cell acanthoma vs. Psoriasis, plaque expression

Hamartomas (“congenital” melanocytic nevi) and benign neoplasms (“acquired” melanocytic nevi) of various specific types, all of which are composed of abnormal melanocytes and manifested clinically as lesions of different colo…

Differential Diagnosis in Dermatopathology

Trichoepithelioma vs. Infundibulocystic basal-cell carcinoma

Hamartomas (“congenital” melanocytic nevi) and benign neoplasms (“acquired” melanocytic nevi) of various specific types, all of which are composed of abnormal melanocytes and manifested clinically as lesions of different colo…

Dermatology Practical & Conceptual

Large cell acanthoma: a debate throughout the decades

Have we really concluded what a large cell acanthoma is? Is it a distinct entity, a solar lentigo, a subtype of seborrheic keratosis, or an HPV-induced acanthoma? In 1970, large cell acanthoma (LCA) was first described by Pinkus, as a sharply demarc…

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