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Therapeutic Strategies in Dermatology

Pemphigus Vulgaris: Overview

Overview Because overwhelming evidence suggests a cause-and-effect relationship between pemphigus autoantibody and the disease activity, therapy is aimed at both resolution of cutaneous lesions and elimination of circulating antibody. The titer of t…

Therapeutic Strategies in Dermatology

Lichen Planus: Clinical Cases

…cation Switched to dexamethasone swish/spit: 5 cc t.i.d. (when disease is active) Nystatin troches (used daily to b.i.d.) are also given, to be used with dexamethasone use Disease resolved: minimal flares 1-2 times a year, responsive to dexamethasone…

Therapeutic Strategies in Dermatology

Pediculosis (Lice): Key Points

Key Points Pediculosis, or louse infestation, is a common clinical issue that is of limited morbidity but significant public health concern, especially in school-age children. Humans may be parasitized by three louse types: body lice, head lice, an…

Therapeutic Strategies in Dermatology

Xerosis: Overview

…ed pruritus, and occasionally, nummular dermatitis. The recent onset of generalized xerosis, with or without pruritus, can reflect underlying metabolic or neoplastic disease. Recalcitrant xerosis with secondary pruritus can be the harbinger of system…

Therapeutic Strategies in Dermatology

Photosensitivity Dermatoses: Overview

Photosensitive drug eruptions, polymorphous light eruption, chronic actinic dermatitis (CAD -includes the conditions previously called photosensitive eczema, actinic reticuloid and persistent light reaction). Photosensitivity dermatoses are caused e…

Therapeutic Strategies in Dermatology

Chronic Bullous Disease of Childhood: Overview

…ted disorder, patient comfort rather than total suppression of disease activity is the therapeutic goal. Accept limited disease activity, and do not overtreat with steroids or sulfones in relatively recalcitrant cases. Screen all patients for G6PD ac…

Therapeutic Strategies in Dermatology

Lupus: Clinical Cases

Clinical Cases Case 1 31-year-old woman with recurrent lesions on cheeks and scalp Negative workup for systemic lupus erythematosus (recent) Lesions are itchy, exacerbated by sun exposure No current treatment Initial evaluation Diagnosis: Disc…

Therapeutic Strategies in Dermatology

Cheilitis Granulomatosa: Overview

Melkersson-Rosenthal Syndrome Cheilitis granulomatosa is sudden onset of swelling of the lips which progresses to chronic enlargement. The Melkersson-Rosenthal syndrome diagnosis is made when lip enlargement is accompanied by facial paralysis or par…

Therapeutic Strategies in Dermatology

Borreliosis (Lyme Disease): Clinical Cases

Clinical Cases Case 1 14-year-old teenage girl with a rash on the right lateral cheek present for four days Skin lesion developed three days after a hike through the woods No known history of tick bites Otherwise healthy, feeling well Initial e…

Therapeutic Strategies in Dermatology

Atopic Dermatitis: Clinical Cases

…immunosuppression (such as prednisone or cyclosporine) if the disease is worsening Case 3 Severe disease with superinfection 4-year-old child with long standing atopic dermatitis of the face, trunk, arms, and legs, now presenting with acute ons…

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