Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Fibrosing Dermatitis

…fibrosing inflammation (Fig. 5.357 A&B). The sequence of suppuration, granulomatous inflammation, and fibrosis also is played out dutifully in the aftermath of explosion of an infundibular cyst, a phenomenon that occurs commonly (see Fig. 5.358…

Histologic Diagnosis of Inflammatory Skin Diseases

Cat-scratch disease

…it being found especially in macrophages and free in zones of suppuration and necrosis. Isolation of the organism from the blood of patients has been recorded. Bibliography Bibliography for cat-scratch disease Beato M, Contreras F. Common association…

Histologic Diagnosis of Inflammatory Skin Diseases

Arthropod assaults

…iz 393-6. Shim H, Phelps RG. Intravascular fibrin thrombi and suppuration as a clue to tick bite reaction. J Cutan Pathol. 1997;24:124. (abstract) Zhu YI, Stiller MJ. Arthropods and skin diseases. Int J Dermatol 2002;41:533-49. Bibliography for Wells…

Histologic Diagnosis of Inflammatory Skin Diseases

Infundibulitis secondary to medications systemic

…hose medications topical that induce comedones in addition to suppuration, e.g., ones that are incorporated into an oil base. In short, there is no way to identify with specificity infundibulitis caused by a medication delivered systemically, and, th…

Differential Diagnosis in Dermatopathology

Discussions

…, the epithelial channel is formed always by an infundibulum, suppuration is prominent, elastic fibers in the channel are few if present at all, and, as a, rule only a single focus of change pathologic is encountered in a 4.0 millimeter punched-out b…

Histologic Diagnosis of Inflammatory Skin Diseases

Pattern Analysis in Historical Perspective

…that term is not correct precisely) is extension directly of suppuration from an infundibulum to a follicle seated immediately beneath and in continuity with it, the parts of a true follicle, from top to bottom, being isthmus, stem, and bulb. In sho…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…e fat necrosis in adjacent lobules, followed, in sequence, by suppuration, granulomatous inflammation, and fibrosis. 10.84.2A: Vasculitis, large-vessel, mixed-cell + 10.84.2B: A mix of inflammatory cells, including histiocytes, some of them…

Differential Diagnosis in Dermatopathology

Discussions

…in acne vulgaris it is incidental to the suppurative process. Suppuration is common in papules of acne vulgaris where large abscesses in the dermis are accompanied by evidences of a ruptured infundibulum. In rosacea, there are no large abscesses, onl…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…undibular + 10.27.4B: Innumerable eosinophils in zones of suppuration = Eosinophilic pustular folliculitis Although changes identical with these can be seen in Ofuji’s syndrome, the person from whom this biopsy specimen was taken suffered f…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Changing Mole?

…n infundibular cyst beneath them with subsequent induction of suppuration, granulomatous inflammation, and fibrosis, are examples of changing moles. Moreover, physicians should be alert to the fact that what they instruct patients to conceive of as a…