Histologic Diagnosis of Inflammatory Skin Diseases

Deep fungal infections

…eria (e.g., Staphylococcus) mycobacteria (e.g., Mycobacterium tuberculosis), and algae (e.g., Prototheca). Correlation clinicopathologic Papules and nodules result from dense nodular or diffuse mixed-cell infiltrates that extend throughout much of th…

Differential Diagnosis in Dermatopathology

Discussions

…atus faciei, and acnitis were wrongly presumed to be forms of tuberculosis. Today, those conditions are recognized to be variants of rosacea and to be unrelated to tuberculosis. The mechanisms that lead to development of acne vulgaris, although not u…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Keratosis Lichenoides Chronica?

…n association with a variety of diseases including hepatitis, tuberculosis, glomerulonephritis, and lymphoproliferative diseases has been reported. We present a new case which may have been triggered by trauma or carbamazepine.” Haas N, Czaika…

Differential Diagnosis in Dermatopathology

Acne vulgaris, erythematous papule vs. Rosacea, erythematous papule

…by atypical mycobacteria, that is, mycobacteria other than those responsible for tuberculosis and leprosy, expressed clinically as keratotic and crusted papules, plaques, nodules, and tumors that may be punctuated by draining sinuses and by ulcers….

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Focus of Infection?

…9, vitiligo. Group 3: Those considered in some relation with tuberculosis:            1, erythema induratum; 2, lupus erythematosus; 3, lupus vulgaris; 4, lichen scrofulosorum; 5, various tuberculides. Group 4: Those arising from a focus in the skin…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Wegener’s Granulomatosis?

…nd lungs. To Wegener, the pattern was similar to that seen in tuberculosis and syphilis. He speculated that the granulomatous process began in passages of the upper airway, where chronic inflammation induced hypersensitivity that, in turn, affected b…

Histologic Diagnosis of Inflammatory Skin Diseases

Leishmaniasis

…ep fungal infections, e.g., sporotrichosis and blastomycosis, tuberculosis cutis, and infection by atypical mycobacteria may be indistinguishable Chronic cutaneous leishmaniasis Lupus vulgaris may be indistinguishable Disseminated anergic cutaneous l…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…Erythema induratum (Bazin) is nodular vasculitis in which M. tuberculosis is thought to be the cause. The term should be reserved for those few examples of nodular vasculitis that have been proven to result from infection by that bacterium. 10…