Search Results for: vesicle

Histologic Diagnosis of Inflammatory Skin Diseases

Farmyard pox

…opathologic Cowpox and smallpox also exhibit prominent ballooning of spinous keratocytes, reticular alteration, multilocular vesicles, and eosinophilic inclusion bodies in the cytoplasm of ballooned cells. Those diseases can be differentiated from…

Histologic Diagnosis of Inflammatory Skin Diseases

Pattern Analysis in Historical Perspective

…was designated “intraepidermal vesicular and pustular dermatitis” and because a pustule is very different from a vesicle, both morphologically and conceptually, “pustular dermatitis” now is given its due as a separate, but…

Histologic Diagnosis of Inflammatory Skin Diseases

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…pesvirus infection, fully developed If this lesion had not been interrupted by biopsy, the tension within the intraepidermal vesicle would have caused it to burst and to become subepidermal, too; only a single layer of basal keratocytes remains at…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…is, intraepidermal and subepidermal + 10.44.15B: Acantholytic cells in the spinous layer = Grover’s disease A distinct vesicle in Grover’s disease, like the one shown here, is exceptional. It began intraepidermal and was so tense that it…

Histologic Diagnosis of Inflammatory Skin Diseases

Impetigo contagiosa

…rather than pustular or bullous, and favors the trunk. Herpes simplex may mimic impetigo, particularly when the contents of vesicles become turbid, but lesions tend to be vesicles rather than bullae, and they do not assume figurate outlines. Tinea…

Histologic Diagnosis of Inflammatory Skin Diseases

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….50.4B: Surfeit of eosinophils in the blister and extensive epidermal necrosis = Incontinentia pigmenti, vesicular stage The vesicle in incontinentia pigmenti comes into being as a rule solely by spongiosis. This example is exceptional; ballooning…

Histologic Diagnosis of Inflammatory Skin Diseases

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…mal vesiculation, a phenomenon that also may develop in that condition as a consequence of rupture of a tense intraepidermal vesicle. 10.58.4A: Vasculitis, small-vessel, neutrophilic + 10.58.4B: Neutrophils and nuclear “dust” of…

Histologic Diagnosis of Inflammatory Skin Diseases

Leukocytoclastic vasculitis

…of the papillary dermis and intraepidermal vesicles from a combination of spongiosis and ballooning. A tense intraepidermal vesicle may burst to become subepidermal. By the time vesicles have formed in an epidermis, signs of necrosis usually have…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…is that in foci is hypergranulotic and hyperkeratosis = “Bullous” lichen planus The tiny blister shown here is a vesicle, not a bulla, and it came into being by virtue of the process of lichen planus being accelerated greatly, analogous…