Search Results for: vesicle

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…tiforme The subepidermal blister came into being as a result of rupture of tense intraepidermal vesicles. The intraepidermal vesicles developed mostly as a consequence of ballooning of keratocytes, rather than of spongiosis. 10.32.4A: Vesicular…

Histologic Diagnosis of Inflammatory Skin Diseases

Farmyard pox

…opathologic Cowpox and smallpox also exhibit prominent ballooning of spinous keratocytes, reticular alteration, multilocular vesicles, and eosinophilic inclusion bodies in the cytoplasm of ballooned cells. Those diseases can be differentiated from…

Histologic Diagnosis of Inflammatory Skin Diseases

Impetigo contagiosa

…rather than pustular or bullous, and favors the trunk. Herpes simplex may mimic impetigo, particularly when the contents of vesicles become turbid, but lesions tend to be vesicles rather than bullae, and they do not assume figurate outlines. Tinea…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…is, intraepidermal and subepidermal + 10.44.15B: Acantholytic cells in the spinous layer = Grover’s disease A distinct vesicle in Grover’s disease, like the one shown here, is exceptional. It began intraepidermal and was so tense that it…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Primary and Secondary Lesions?

…ermatology, 2nd ed. Berlin: Springer-Verlag, 2000:9. “Primary lesions: macule, papule, nodule, patch, plaque, pustule, vesicle, bulla (blister), wheal, telangiectasia. Secondary lesions: crust, excoriation, lichenification, lichenoid,…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

….50.4B: Surfeit of eosinophils in the blister and extensive epidermal necrosis = Incontinentia pigmenti, vesicular stage The vesicle in incontinentia pigmenti comes into being as a rule solely by spongiosis. This example is exceptional; ballooning…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…mal vesiculation, a phenomenon that also may develop in that condition as a consequence of rupture of a tense intraepidermal vesicle. 10.58.4A: Vasculitis, small-vessel, neutrophilic + 10.58.4B: Neutrophils and nuclear “dust” of…

Histologic Diagnosis of Inflammatory Skin Diseases

Leukocytoclastic vasculitis

…of the papillary dermis and intraepidermal vesicles from a combination of spongiosis and ballooning. A tense intraepidermal vesicle may burst to become subepidermal. By the time vesicles have formed in an epidermis, signs of necrosis usually have…