Differential Diagnosis in Dermatopathology

Differential Diagnosis

Xanthogranuloma Necrobiotic xanthogranuloma 1. Surface domed 1. Surface flat 2. Infiltrate often well circumscribed 2. Infiltrate poorly circumscribed 3. Infiltrate often embraced partially by collarettes of epithelium 3. No collarettes of e…

Differential Diagnosis in Dermatopathology

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Xanthogranuloma Necrobiotic xanthogranuloma

Differential Diagnosis in Dermatopathology

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Necrobiosis lipoidica Necrobiotic xanthogranuloma

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Necrobiosis lipoidica Necrobiotic xanthogranuloma 1. Infiltrates of inflammatory cells equally dense throughout the dermis or “top-heavy” 1. Infiltrates of inflammatory cells “bottom-heavy” 2. Septal panniculitis with s…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Xanthogranuloma Reticulohistiocytic granuloma 1. Cytoplasm of histiocytes foamy usually; not usually finely granular 1. Cytoplasm of histiocytes finely granular usually; foamy sometimes 2. Cytoplasm of histiocytes usually abundant, pale, and d…

Dermatology Practical & Conceptual

Yellow color upon dermatoscopy does not exclude melanoma!

In this issue, Rosendahl and colleagues report a case of non-choroidal melanoma that shows a strikingly unusual dermatoscopic aspect, namely, structureless yellow color. The authors correlate the yellow color to the presence of lipofuscin using tiss…

Differential Diagnosis in Dermatopathology

Images

Xanthogranuloma Reticulohistiocytic granuloma…