Histologic Diagnosis of Inflammatory Skin Diseases

Crohn’s disease

Crohn’s disease Synonyms Inflammatory bowel disease Regional ileitis Regional enteritis Chronic cicatrizing enteritis Presentation stereotypical Age and sex Young adults; slight predominance of women Distribution of lesions The poles of the ga…

Histologic Diagnosis of Inflammatory Skin Diseases

Factitious dermatitis and panniculitis

Factitious dermatitis and panniculitis Synonyms Self-induced skin disease Pathomimicry Dermatitis artifacta Munchhausen syndrome Dermatitis passivata Factitial lymphedema (Secretan syndrome) Malingering Self-mutilation Presentation stereotypical Age…

Differential Diagnosis in Dermatopathology

Trichoadenoma vs. Microcystic adnexal carcinoma

A malignant neoplasm of melanocytes that, in the skin, begins as a macule and may become a patch or a papule. A flat lesion of melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly…

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema figuratum

Erythema figuratum Synonyms Erythema figuratum perstans Figurate erythema Annular erythema Presentation stereotypical Age and sex Adults of both sexes, but women especially Distribution of lesions Localized or widespread, trunk and proximal extremit…

Differential Diagnosis in Dermatopathology

Discussions

Nevus verrucosus and acanthosis nigricans are processes that affect the papillary dermis and the epidermis. Both conditions may display hyperkeratosis, epidermal hyperpigmentation, papillomatosis, melanophages, and an increased number of fibrocytes…

Differential Diagnosis in Dermatopathology

Images

Metastatic carcinoma from a breast Morpheiform basal-cell carcinoma…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Metastatic carcinoma from a breast Morpheiform basal-cell carcinoma 1. Strands, cords, and columns of neoplastic epithelial cells in the dermis 1. Cords and columns of neoplastic epithelial cells in the dermis; no strands as a rule 2. Differen…

Differential Diagnosis in Dermatopathology

Discussions

A proliferation of keratocytes that simulates squamous-cell carcinoma and authentic squamous-cell carcinoma itself have findings histopathologic in common, including epithelial cells that cornify, nuclei of epithelial cells that are not entirely typ…

Histologic Diagnosis of Inflammatory Skin Diseases

Keloid

Keloid Presentation stereotypical Age and sex Young adults especially, both sexes, more often in darkly pigmented individuals, especially Africans and African-Americans Distribution of lesions Sternal region, ear lobes, shoulders, and the upper part…