Search Results for: necrobiosis

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Vasculitis

…septa in the subcutaneous fat) of a still-evolving lesion of necrobiosis lipoidica, of Wegener’s granulomatosis, and of Crohn’s disease. Figure 5.219 A&B. “Lymphocytic vasculitis”: an epiphenomenon. So-called lymphocytic…

Histologic Diagnosis of Inflammatory Skin Diseases

Introduction

…ery incipient stage of those diseases, and for distinguishing necrobiosis lipoidica from morphea at a very late “burned out” stage. The terms “anetoderma,” “poikiloderma,” and “lipodystrophy,” unmodifie…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Necrotizing Vasculitis?

…gmented epithelioid melanocytomas,” dyshidrosis,” necrobiosis,” eczema,” etc., etc., etc. “The necrotizing vasculitides include a variety of clinical disorders associated with segmental inflammation and necrosis of the b…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Perivasculitis?

…necrobiotic areas in all 3 cases. . . . We propose that both necrobiosis and granulomatous perivasculitis be added to the histopathologic characteristics of metastatic Crohn’s disease.” Hackzell-Bradley M. Hedblad MA, Stephansson EA. Met…

Histologic Diagnosis of Inflammatory Skin Diseases

Livedo vasculitis

…athy because it is bereft of meaning as terms such as eczema, necrobiosis, hyalin, “dysplasia,” “architectural disorder,” and “neoplasm of uncertain biologic potential.” Moreover, livedo vasculitis fulfills criteri…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Perforating Diseases?

…ed to occur in dermal diseases, including granuloma annulare, necrobiosis lipoidica diabeticorum, and pseudoxanthoma elasticum.” Turkington C, Dover JS, eds. The Encyclopedia of Skin and Skin Disorders, 2nd ed. New York: Facts On File, Inc, 200…

Differential Diagnosis in Dermatopathology

Images

Granuloma annulare Necrobiosis lipoidica…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Granuloma annulare Necrobiosis lipoidica 1. Epidermis not thinned 1. Epidermis usually thinned with effacement of rete ridges 2. Upper part of the reticular dermis usually more involved than the lower part; subcutaneous fat spared in papules 2. Low…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Necrobiosis lipoidica Necrobiotic xanthogranuloma 1. Infiltrates of inflammatory cells equally dense throughout the dermis or “top-heavy” 1. Infiltrates of inflammatory cells “bottom-heavy” 2. Septal panniculitis with slight…