Search Results for: necrobiosis

Histologic Diagnosis of Inflammatory Skin Diseases

Introduction

…of erythema multiforme vis-a-vis Mucha-Habermann disease at a very incipient stage of those diseases, and for distinguishing necrobiosis lipoidica from morphea at a very late “burned out” stage. The terms “anetoderma,”…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Necrotizing Vasculitis?

…splastic nevus,” “animal melanoma,” “pigmented epithelioid melanocytomas,” dyshidrosis,” necrobiosis,” eczema,” etc., etc., etc. “The necrotizing vasculitides include a variety of clinical…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Perivasculitis?

…nifested as granulomatous perivasculitis in both. We also found necrobiotic areas in all 3 cases. . . . We propose that both necrobiosis and granulomatous perivasculitis be added to the histopathologic characteristics of metastatic Crohn’s…

Histologic Diagnosis of Inflammatory Skin Diseases

Livedo vasculitis

…ulopathy and not a true vasculitis. We eschew the term vasculopathy because it is bereft of meaning as terms such as eczema, necrobiosis, hyalin, “dysplasia,” “architectural disorder,” and “neoplasm of uncertain…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Perforating Diseases?

…ulitis, Kyrle’s disease. Perforation has also been reported to occur in dermal diseases, including granuloma annulare, necrobiosis lipoidica diabeticorum, and pseudoxanthoma elasticum.” Turkington C, Dover JS, eds. The Encyclopedia of…

Differential Diagnosis in Dermatopathology

Images

Granuloma annulare Necrobiosis lipoidica

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Granuloma annulare Necrobiosis lipoidica 1. Epidermis not thinned 1. Epidermis usually thinned with effacement of rete ridges 2. Upper part of the reticular dermis usually more involved than the lower part; subcutaneous fat spared in papules 2….

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Necrobiosis lipoidica Necrobiotic xanthogranuloma 1. Infiltrates of inflammatory cells equally dense throughout the dermis or “top-heavy” 1. Infiltrates of inflammatory cells “bottom-heavy” 2. Septal panniculitis with…