Differential Diagnosis in Dermatopathology

Lichen planus vs. Lichen planus-like keratosis

…osis and radiation keratosis, are euphemisms for various types of superficial squamous cell carcinoma. Very episodically, neoplastic cells of those types of squamous cell carcinoma proliferate wildly, and the primary neoplasm then consists of aggrega…

Differential Diagnosis in Dermatopathology

Discussions

…becomes associated with a dense lichenoid infiltrate composed of lymphocytes especially. The keratosis usually is sampled by biopsy using the shave excision technique, and the lesion generally is seen to extend from one edge of the section to the ot…

Differential Diagnosis in Dermatopathology

Lichen planus vs. Lichenoid discoid lupus erythematosus

…osis and radiation keratosis, are euphemisms for various types of superficial squamous cell carcinoma. Very episodically, neoplastic cells of those types of squamous cell carcinoma proliferate wildly, and the primary neoplasm then consists of aggrega…

Differential Diagnosis in Dermatopathology

Leukocytoclastic vasculitis vs. livedo vasculitis

…osis and radiation keratosis, are euphemisms for various types of superficial squamous cell carcinoma. Very episodically, neoplastic cells of those types of squamous cell carcinoma proliferate wildly, and the primary neoplasm then consists of aggrega…

Differential Diagnosis in Dermatopathology

Discussions

…ith leukocytoclastic vasculitis. In truth, there are a variety of “palpable purpuras” in the skin other than leukocytoclastic vasculitis, for example, the lichenoid purpura of Gougerot and Blum (lichen aureus), purpuric papules of Mucha-H…

Differential Diagnosis in Dermatopathology

Images

Lichenoid purpura (of Gougerot and Blum) Mycosis fungoides (plaque stage)…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Lichenoid purpura (of Gougerot and Blum) Mycosis fungoides (plaque stage) 1. Epidermis usually normal or slightly acanthotic 1. Epidermis often psoriasiform 2. No lymphocytes disposed as solitary units in the epidermal basal layer 2. Lymphocyt…

Histologic Diagnosis of Inflammatory Skin Diseases

Leukocytoclastic vasculitis

…ty, palpable purpura may be seen in lesions as varied as those of the lichenoid purpura of Gougerot and Blum (lichen aureus), Mucha-Habermann disease, and a hematoma. In short, rather than designating lesions of leukocytoclastic vasculitis “urt…

Histologic Diagnosis of Inflammatory Skin Diseases

Lymphocytoma cutis

…a burgdorferi, and to injected foreign materials, such as that of tattoos Simulators of T-cell lymphoma, e.g., Lymphomatoid drug eruption
Lymphomatoid contact dermatitis
Lichenoid purpura of Gougerot and Blum
Various inflammatory diseases episodicall…

Differential Diagnosis in Dermatopathology

Discussions

…ough there are many conditions marked by lichenoid infiltrates of lymphocytes besides lichen planus and discoid lupus erythematosus (for example, lichenoid photodermatitis, lichenoid drug eruptions, lichenoid purpura of Gougerot and Blum, and lichen…