Differential Diagnosis in Dermatopathology

Differential Diagnosis

Tuberculoid leprosy Sarcoidosis 1. Oblong aggregations made up of epithelioid histiocytes 1. Roundish aggregations composed of epithelioid histiocytes 2. Granulomas predominantly in the lower part of the dermis, less often in the upper part al…

Histologic Diagnosis of Inflammatory Skin Diseases

Necrobiotic xanthogranuloma

Necrobiotic xanthogranuloma Presentation stereotypical Age and sex Middle-aged and older persons of both sexes Distribution of lesions Periorbital region particularly, but trunk, extremities, and neck sometimes affected Individual lesions Papules, n…

Differential Diagnosis in Dermatopathology

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Tuberculoid leprosy Sarcoidosis

Histologic Diagnosis of Inflammatory Skin Diseases

Granuloma annulare

Granuloma annulare Presentation stereotypical Age and sex Any age in both sexes Distribution of lesions Localized, often to extensor aspects of extremities, or widespread Configuration of lesions Annular, sometimes arcuate Arrangement of lesions Sca…

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema figuratum

Erythema figuratum Synonyms Erythema figuratum perstans Figurate erythema Annular erythema Presentation stereotypical Age and sex Adults of both sexes, but women especially Distribution of lesions Localized or widespread, trunk and proximal extremit…

What is Rosacea?

What is Rosacea?

Rosacea is a common inflammatory facial skin disorder classically marked by flushing, facial erythema, inflammatory papules and pustules, and telangiectasias. It typically presents in adults, with prevalence reported as 1 to greater than 20%, with a…

Histologic Diagnosis of Inflammatory Skin Diseases

Miescher’s granuloma of the face

Miescher’s granuloma of the face Presentation stereotypical Age and sex Women Distribution of lesions Face and scalp Configuration of lesions Annular Individual lesions Plaques Course Resolving after many months Differential diagnosis clinical…

Histologic Diagnosis of Inflammatory Skin Diseases

Hypodermitis sclerodermiformis

Hypodermitis sclerodermiformis Synonyms Hypodermatitis sclerodermiformis Hypodermitis sclerositans Liposclerosis Lipodermatosclerosis Stasis dermatosclerosis Sclerotic panniculitis Sclerosing panniculitis Presentation stereotypical Age and sex Adult…

Histologic Diagnosis of Inflammatory Skin Diseases

Leukocytoclastic vasculitis

Leukocytoclastic vasculitis Synonyms Leukocytoclastic angiitis Allergic vasculitis Hypersensitivity angiitis Hypersensitivity vasculitis Anaphylactoid purpura Immune complex vasculitis Purpura rheumatica Presentation stereotypical Age and sex Any ag…

Histologic Diagnosis of Inflammatory Skin Diseases

Lupus erythematosus

Lupus erythematosus Synonyms Lupus erythematodes Presentation stereotypical Age and sex Young adult women especially, but sometimes neonates and older persons of both sexes. Distribution of lesions Often localized to sun-exposed sites such as the fa…