Histologic Diagnosis of Inflammatory Skin Diseases

Majocchi’s granuloma

Majocchi’s granuloma Synonyms Nodular granulomatous perifolliculitis Tinea der unterschenkel Perifollicular granuloma Trichophytic granuloma Comment The term “Majocchi’s granuloma” is misleading because it implies that the…

Histologic Diagnosis of Inflammatory Skin Diseases

Infundibulitis secondary to medications systemic

Infundibulitis secondary to medications systemic Comment Findings histopathologic in infundibulitis secondary to medications administered systemically are no different from those in suppurative infundibulitis of any noninfectious cause, with the exc…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.84.1A: Vasculitis, large-vessel, mixed cell + 10.84.1B: Thrombus within the lumen of an artery situated in the subcutaneous fat and a mix of inflammatory cells in the wall of it = Polyarteritis nodosa ┬áThe infiltrate of inflamma…

Dermatology Practical & Conceptual

A verrucous plaque on the lower leg

Quiz case A 52-year-old male patient from South Africa presented with a lesion on his lower left leg extending from the ankle to just below the knee that has been present for twenty years. The lesion first developed as a verrucous nodule close to th…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.79.1A: Diffuse dermatitis, neutrophils predominant, and panniculitis, lobular + 10.79.1B: Brown fungi characterized by a thick wall = Phaeohyphomycosis ┬áThis condition is a subcutaneous variant of chromomycosis. Fungi reside mos…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…usually is present at the base of the epithelial channel 6. Suppuration present within the infundibular channel and sometimes contiguous with it 6. Neutrophils variable in number in the channels, i.e., sparse to moderately dense, but rarely as sup…

Histologic Diagnosis of Inflammatory Skin Diseases

Pheohyphomycosis

Pheohyphomycosis Synonyms Phaeomycotic cyst Subcutaneous pheaohyphomycosis Presentation stereotypical Age and sex No predilection for age or sex, but more common in individuals who reside in the tropics; most of those persons not immunocompromised…

Histologic Diagnosis of Inflammatory Skin Diseases

Nodular fasciitis

Nodular fasciitis Synonyms Proliferative fasciitis Subcutaneous pseudocarcinomatous fibromatosis Presentation stereotypical Age and sex Young adults of both sexes Distribution of lesions Localized to extremities, forearms mostly, in adults, but to…

Histologic Diagnosis of Inflammatory Skin Diseases

Crohn’s disease

Crohn’s disease Synonyms Inflammatory bowel disease Regional ileitis Regional enteritis Chronic cicatrizing enteritis Presentation stereotypical Age and sex Young adults; slight predominance of women Distribution of lesions The poles of the ga…

Differential Diagnosis in Dermatopathology

Discussions

Nodular vasculitis and subcutaneous polyarteritis nodosa are inflammatory diseases that affect medium-sized and large arteries situated in fibrous septa of the subcutaneous fat. Both conditions involve the subcutaneous fat mostly, although signs of…