Histologic Diagnosis of Inflammatory Skin Diseases

Images

…rential diagnosis is lichen scrofulosorum, a manifestation of tuberculosis. 10.59.4A: Perivascular dermatitis, lichenoid, focal + 10.59.4B : Lymphocytes intermingled with epithelioid histiocytes = Lichen nitidus The findings at scanning mag…

Histologic Diagnosis of Inflammatory Skin Diseases

Behçet’s Disease

…not comparable to any reaction seen usually in patients with tuberculosis, and he noted that even when he injected water alone just beneath the surface of the skin, the same phenomenon occurred. The lesion that developed at the site of injection was…

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema nodosum leprosum

…se chain reaction dot-blotting system for detecting cutaneous tuberculosis. Br J Dermatol 2000;142(1):72-76. Coruh G, McDougall AC. Untreated lepromatous leprosy: histopathological findings in cutaneous blood vessels. Int J Lepr Other Mycobact Dis 19…

Differential Diagnosis in Dermatopathology

Discussions

…ulitis was thought, in former times, to be a manifestation of tuberculosis, i.e., a “tuberculid,” and was named erythema induratum. Nowadays, tuberculous cause is rare for skin diseases of any kind, including nodular vasculitis. That bein…

Differential Diagnosis in Dermatopathology

Discussions

…thought in times former to be a manifestation of disseminated tuberculosis because of extensive granulomatous and necrotizing inflammation reminiscent of infection by tubercle bacilli. In those days, the condition was termed “erythema induratum…

Histologic Diagnosis of Inflammatory Skin Diseases

Crohn’s disease

…hat are out of place, e.g., hair shafts lodged in the dermis. Tuberculosis is typified by tuberculoid granulomas punctuated often by caseous necrosis in the center of them. Sarcoidosis usually is not accompanied by dense infiltrates of lymphocytes ar…

Differential Diagnosis in Dermatopathology

Nodular vasculitis vs. Subcutaneous polyarteritis nodosa

…by atypical mycobacteria, that is, mycobacteria other than those responsible for tuberculosis and leprosy, expressed clinically as keratotic and crusted papules, plaques, nodules, and tumors that may be punctuated by draining sinuses and by ulcers….

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema nodosum

…those of infectious agents, e.g., streptococci, Mycobacteria tuberculosis, yersinia, histoplasma, coccidioides, and blastomyces; drugs, e.g., oral contraceptives; malignant neoplasms, e.g., lymphoma and leukemia; and whatever is responsible for sarc…

Differential Diagnosis in Dermatopathology

Erythema nodosum vs. Nodular vasculitis

…by atypical mycobacteria, that is, mycobacteria other than those responsible for tuberculosis and leprosy, expressed clinically as keratotic and crusted papules, plaques, nodules, and tumors that may be punctuated by draining sinuses and by ulcers….