Search Results for: necrobiosis

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Pseudopelade?

…impede clinicians and histopathologists from coming to diagnoses with specificity. Chief among those are eczema, dysplasia, necrobiosis, parapsoriasis, and pseudopelade. None of those words is necessary because none has specificity. If the aim of…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Granuloma annulare Necrobiosis lipoidica 1. Epidermis not thinned 1. Epidermis usually thinned with effacement of rete ridges 2. Upper part of the reticular dermis usually more involved than the lower part; subcutaneous fat spared in papules 2….

Differential Diagnosis in Dermatopathology

Images

…Granuloma annulare Necrobiosis lipoidica…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Necrobiosis lipoidica Necrobiotic xanthogranuloma 1. Infiltrates of inflammatory cells equally dense throughout the dermis or “top-heavy” 1. Infiltrates of inflammatory cells “bottom-heavy” 2. Septal panniculitis with…

Differential Diagnosis in Dermatopathology

Images

Necrobiosis lipoidica Necrobiotic xanthogranuloma…

Histologic Diagnosis of Inflammatory Skin Diseases

Granuloma annulare

…histiocytes at the periphery have thin nuclei; fibrosis may be present around palisaded granulomas of longstanding lesions. Necrobiosis lipoidica, in early lesions, exhibits degenerated collagen bundles in the center of palisaded granulomas and in…

Histologic Diagnosis of Inflammatory Skin Diseases

Hypodermitis sclerodermiformis

…mbophlebitis may be manifested as a painful, erythematous, and swollen leg, but often by an indurated cord that is palpable. Necrobiosis lipoidica involves predominantly the region of anterior tibiae and is typified by a yellow cast surrounded by an…

Histologic Diagnosis of Inflammatory Skin Diseases

Leishmaniasis

…dant blue-gray cytoplasm, the analogue in sections stained by hematoxylin and eosin of globi revealed by Fite’s stain. Necrobiosis lipoidica is typified by granulomatous inflammation in the reticular dermis and in the septa of the subcutaneous…