Search Results for: psoriasis

Differential Diagnosis in Dermatopathology

Discussions

Psoriasis and nummular dermatitis share several attributes histopathologic, namely, parakeratosis that often is accompanied by serum, psoriasiform acanthosis, spongiosis, edema of the papillary dermis, and an infiltrate of lymphocytes mostly around…

Histologic Diagnosis of Inflammatory Skin Diseases

Mycosis fungoides

…ar person ever displays. Variations clinical Large-plaque parapsoriasis presents itself as patches, sometimes more than 10 cm in diameter, situated especially on thighs and buttocks, but also at times on the trunk. When it is associated with a yellow…

Histologic Diagnosis of Inflammatory Skin Diseases

Syphilis

…phocytes, rather than mostly of histiocytes and plasma cells. Psoriasis lacks plasma cells and histiocytes, and usually involves the superficial plexus only. Granuloma annulare, unlike juxta-articular nodes, exhibits mucin in association with histioc…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…tuous capillaries in dermal papillae, and no microorganisms = Psoriasis, pustular In infundibular epidermis: + Bacteria = Bacterial infundibulitis + Hyphae = Majocchi”s granuloma + No infectious agents = Any noninfectious suppurative infundibul…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…cale-crust that house neutrophils are reminiscent of those in psoriasis, the absence of dilated tortuous capillaries in thin dermal papillae and of elongated rete ridges of about even length militates against that diagnosis. 10.98.4A: Perivascular de…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Keratosis Lichenoides Chronica?

…thematosus, pityriasis lichenoides, pityriasis rubra pilaris, psoriasis, mycosis fungoides, or lichen simplex chronicus, but an authentic and distinctive condition that seems to be exceedingly rare. Cause and pathogenesis of it are not known, the cou…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Colors Stereotypical for Diseases Specific?

…whitish blue of argyria, and depigmented scars are examples. Psoriasis scales have a peculiar silvery tinge. Pink and red lesions are usually inflammatory, excepting in nevi, and red tattooing. Yellow and orange lesions are found in xanthoma, and th…

Differential Diagnosis in Dermatopathology

Discussions

The erythroderma of psoriasis and the erythroderma of mycosis fungoides have several attributes histopathologic in common: psoriasiform acanthosis, an infiltrate in the dermis that consists mostly of lymphocytes and is situated especially around and…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…the epidermis and papillary dermis resembles closely that of psoriasis, but the combination of lichenoid infiltration and numerous lymphocytes in the epidermis militates against psoriasis and indicates mycosis fungoides. 11.14.3A: Nodular dermatosis…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…= Dermatophytosis Infection by superficial fungi may simulate psoriasis, as is the case here, the crucial attribute differentiating being the presence of hyphae, those being seen better when stained by PAS. 10.22.3A: Pustular dermatitis, surface epid…