Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ilaris never is as prominent as in a fully developed lesion of psoriasis, and, unlike the situation in psoriasis, rete ridges and suprapapillary plates are not thin. 10.82.3A: Perivascular dermatitis, psoriasiform + 10.82.3B: Pallor in the…

Histologic Diagnosis of Inflammatory Skin Diseases

Mycosis fungoides

Mycosis fungoides Synonyms Cutaneous T-cell lymphoma Presentation stereotypical Age and Sex Adults usually, although children may be affected. Males preponderant. Distribution of lesions Often widespread, but sometimes localized to a single patch or…

Histologic Diagnosis of Inflammatory Skin Diseases

Syphilis

…and granular zones, and at summit of mounds of parakeratosis. Psoriasis is typified by a superficial infiltrate of lymphocytes, rather than a superficial and deep infiltrate of histiocytes and plasma cells. Moreover, the infiltrate in psoriasis is n…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

In this section, algorithms used to reach specific diagnosis are predicated on “nonspecific” findings recognized best at higher magnification. Other changes requisite for specific diagnoses, i.e., denominators that are essential, then ar…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.98.1A: Perivascular dermatitis, and infundibulitis, spongiotic + 10.98.1B: Predominance of lymphocytes and scale-crusts at lips of infundibular ostia = Seborrheic dermatitis ┬áMounds of scale-crust at lips of infundibular ostia a…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Keratosis Lichenoides Chronica?

“So we have to start once more [in regard to what is the authentic nature of lichen rubra moniliformia], returning to the old case of Kaposi by which the question began in 1886.” Pinkus H. Lichen ruber moniliformis Kaposi. Arch Dermato…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Colors Stereotypical for Diseases Specific?

…kin on the color of lesions cutaneous. For example, lesions of psoriasis in Africans, especially when situated on the legs, are purple, and if an observer is not aware of that phenomenon, misinterpretation of psoriasis as lichen planus is a pitfall p…

Differential Diagnosis in Dermatopathology

Discussions

…the consideration of dermatophytosis, the changes in eruptive psoriasis are diagnostic of that condition. Fully developed lesions of psoriasis are marked by confluent parakeratosis with neutrophils layered in the abnormal cornified layer, thinned su…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Parapsoriasis?

“Parapsoriasis. Under this provisional name, Brocq in 1902 grouped several rare and unclassifiable dermatological types, characterized by nonpruriginous erythmato-squamous spots, extremely persistent and rebellious to all treatment. It is ex…

Histologic Diagnosis of Inflammatory Skin Diseases

Seborrheic dermatitis

Seborrheic dermatitis Synonyms Seborrhoeic dermatitis Seborrheic eczema Unna disease Presentation stereotypical Age and sex Young adults especially and males in particular Distribution of lesions Face, scalp, retroauricular area, and V region of the…