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Dermatology Practical & Conceptual

Balloon cell melanoma in primary care practice: a case report

…matopathologically the differential diagnosis includes balloon cell change in benign nevi, clear cell sarcoma, clear cell metastatic renal cell carcinoma, basal cell carcinoma, squamous cell carcinoma, malignant clear cell acrospiroma, sebaceous carc…

Differential Diagnosis in Dermatopathology

"Pseudolymphoma," B-cell type vs. Malignant lymphoma, B-cell type

Extramammary Paget’s disease is an apocrine carcinoma that begins within the epidermis and presents itself clinically as a patch or a subtle plaque that extends centrifugally for many years before becoming a readily discernible thick plaque, a…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Langerhans’ Cell Granulomatosis?

…is represent pathologic, or at least, not “normal” cells, which is difficult to accept. If, on the other hand, the LC is considered a specific histiocytic cell which normally occurs within the connective tissues and within stratified squa…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Cutaneous T-cell Lymphoma?

…(CTCL), also known as mycosis fungoides, consists of malignant cells that resemble mature T cells. Vargo N. Cutaneous malignancies: KA, CTCL, and KS. Dermatol Nurs. 2006;18(3):270,277. New designations for diseases do not always represent an advanc…

Histologic Diagnosis of Inflammatory Skin Diseases

Adult T-cell leukemia/Lymphoma

Adult T-cell leukemia/Lymphoma Presentation stereotypical Age and sex No predilection for sex. Middle-aged individuals from southern Japan and Caribbean Islands. Distribution of lesions Widespread Arrangement Scattered discrete lesions Individual le…

Dermatology Practical & Conceptual

Langerhans cell histiocytosis-a case report

…e sampled for histopathologic examination and revealed a dense cellular infiltrate made up of mononuclear cells with conspicuous eosinophilic cytoplasm and large cleaved vesicular nucleus, some of them with shapes resembling the format of a kidney an…

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