Search Results for: vesicle

Histologic Diagnosis of Inflammatory Skin Diseases

Fixed drug eruption

…mal vesicles Marked spongiosis and ballooning; if ballooning extensive sufficiently, reticular alteration and intraepidermal vesicles ensue Intraepidermal and subepidermal vesiculation may occur together Lymphocytes in association with neutrophils…

Differential Diagnosis in Dermatopathology

Insect "bite" vs. Lymphomatoid papulosis

A blistering inflammatory disease in which acantholysis occurs in the upper part of the spinous zone or granular zone of the epidermis, the result of the process being flaccid blisters that give way to erosions and crusts accompanied by erythema….

Differential Diagnosis in Dermatopathology

Discussions

…dense, superficial and deep, perivascular and interstitial, and comprised mostly of lymphocytes and eosinophils. Spongiotic vesicles may develop in the epidermis. A nodule of scabies is different, clinically and histopathologically, from a papule…

Differential Diagnosis in Dermatopathology

Discussions

…lesions of herpes simplex have been likened to dew drops poised on a petal of a rose, i.e., small, tense, often umbilicated vesicles grouped on a red base. An individual vesicle of herpes simplex is indistinguishable from one of zoster or…

Histologic Diagnosis of Inflammatory Skin Diseases

Prurigo pigmentosa

…rphologic are singular. Clinically, prurigo pigmentosa presents itself as extraordinarily pruritic urticarial papules, papulovesicles, and vesicles arranged in reticulate pattern and distributed symmetrically on the chest, neck, and back, where it…

Differential Diagnosis in Dermatopathology

Nodular scabies vs. Lymphomatoid papulosis

A blistering inflammatory disease in which acantholysis occurs in the upper part of the spinous zone or granular zone of the epidermis, the result of the process being flaccid blisters that give way to erosions and crusts accompanied by erythema….

Differential Diagnosis in Dermatopathology

Herpes simplex vs. Vaccinia

A blistering inflammatory disease in which acantholysis occurs in the upper part of the spinous zone or granular zone of the epidermis, the result of the process being flaccid blisters that give way to erosions and crusts accompanied by erythema….

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema multiforme

…nd individual necrotic keratocytes. Sometimes, the infiltrate of lymphocytes even may qualify as being lichenoid. When tense vesicles and bullae are biopsied, they may exhibit well-defined ballooning of spinous keratocytes in association with…

Histologic Diagnosis of Inflammatory Skin Diseases

Incontinentia pigmenti

…rked by spongiosis that is accompanied by eosinophils, but the number of eosinophils is relatively few compared with that in vesicles of incontinentia pigmenti, and frank spongiotic vesicles come into being rarely. Bullous pemphigoid and herpes…