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Terms of Use

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Histologic Diagnosis of Inflammatory Skin Diseases

Incontinentia pigmenti

…. Laboratory confirmation Genetic mapping for mutations in the Xp I I.21 or the Xq28 locus. Cause and mechanism This hereditary systemic disease is caused by an X-linked genetic defect in loci Xp I I.21 or Xq28, which is dominant in females and usual…

Differential Diagnosis in Dermatopathology

Nodular vasculitis vs. Subcutaneous polyarteritis nodosa

An inflammatory disease caused by the spirochete Borrelia burgdorferi that manifests itself in the skin as erythematous lesions with figurate shapes, e.g., (round, ellipsoid, and arcuate) (erythema chronicum migrans), pseudolymphomatous nodules (lym…

Dermatology Practical & Conceptual

Yellow color upon dermatoscopy does not exclude melanoma!

In this issue, Rosendahl and colleagues report a case of non-choroidal melanoma that shows a strikingly unusual dermatoscopic aspect, namely, structureless yellow color. The authors correlate the yellow color to the presence of lipofuscin using tiss…

Histologic Diagnosis of Inflammatory Skin Diseases

Lupus erythematosus

Lupus erythematosus Synonyms Lupus erythematodes Presentation stereotypical Age and sex Young adult women especially, but sometimes neonates and older persons of both sexes. Distribution of lesions Often localized to sun-exposed sites such as the fa…

Histologic Diagnosis of Inflammatory Skin Diseases

Pemphigus foliaceus

Pemphigus foliaceus Presentation stereotypical Age and sex Adults usually and of both sexes Distribution of lesions Localized to photodistribution in pemphigus erythematosus; widespread in pemphigus foliaceus Individual lesions Macules, patches, fla…

Differential Diagnosis in Dermatopathology

Discussions

Interstitial granulomatous dermatitis with arthritis, a distinctive disease that appears usually in patients with rheumatoid-like arthritis, has many attributes in common with the mostly interstitial type of granuloma annulare. Lesions of both condi…