Search Results for: ballooning

Differential Diagnosis in Dermatopathology

Discussions

…n by firm oblique pressure against apparently normal skin, is elicitable readily. Because the blisters develop consequent to ballooning mostly and/or to severe vacuolar alteration at the dermoepidermal junction and are huge, excessive loss of fluids…

Histologic Diagnosis of Inflammatory Skin Diseases

The Algorithmic Method

…ermis, namely, at the dermoepidermal interface (interface dermatitis) (see Figs. 5.18 and 5.19) and of the epidermis itself (ballooning [see Fig. 5.20], spongiotic [see Fig. 5.21], and psoriasiform dermatitis [see Fig. 5.22]), and each of those can…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…eutrophils in zones of epidermal necrosis, in foci of parakeratosis, and in scale-crusts 6. Vesiculation common secondary to ballooning and/or spongiosis 6. Vesiculation uncommon, but secondary to ballooning mostly rather than spongiosis 7….

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Dermal and Epidermal Types of Erythema Multiforme?

…ny with a sprinkling of lymphocytes, and in which the epidermis is punctuated by numerous necrotic keratocytes and marked by ballooning and spongiosis. Bullous pemphigoid also is a single process in which eosinophils tend to predominate in the…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…necrotic keratocytes = Herpesvirus infection, near fully developed The sequence of events in the epidermis was extraordinary ballooning of keratocytes that led to intraepidermal vesiculation accompanied by reticular alteration of the spinous zone…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…arakeratosis in resolving lesions 2. Psoriasiform acanthosis in time 2. No psoriasiform acanthosis 3. Spongiosis, but little ballooning, in the epidermis 3. Ballooning, but little spongiosis, in the epidermis 4. Very few, if any, individual necrotic…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Mucha-Habermann Disease a Lymphocytic Vasculitis?

…alteration there, and they are present, too, in an epidermis punctuated by individual necrotic keratocytes, spongiosis, and ballooning. In lesions evolving, mounds of parakeratosis house neutrophils. Erythrocytes are extravasated in the papillary…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…stinguished from those of graft-versus-host disease. The paucity of the infiltrate of lymphocytes and confinement of necrotic keratocytes to the lower part of the epidermis in the absence of either spongiosis or ballooning militate against erythema…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…anges are indistinguishable from those in orf. A clue to the diagnosis of this particular viral infection is the presence of ballooning in company with spongiosis, of incipient reticular alteration and necrosis of keratocytes, and of neutrophils in…