Differential Diagnosis in Dermatopathology

Differential Diagnosis

Xanthomatous dermatofibroma Xanthomatous malignant fibrous histiocytoma 1. Lesion relatively well circumscribed 1. Lesion poorly circumscribed 2. No collarettes of epithelium 2. Collarettes of epithelium sometimes 3. Epidermis hyperpigmen…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Dermatofibroma Desmoplastic Spitz’s nevus 1. Acanthotic epidermis often associated with induction of folliculo-sebaceous units 1. Little or no acanthosis; no induction of folliculo-sebaceous units 2. Epidermis often thinned above the cen…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Surface of dermatofibroma affiliated with follicular germs Surface of superficial basal-cell carcinoma 1. Acanthotic hyperpigmented epidermis; not ulcerated 1. Thin epidermis; sometimes eroded and/or ulcerated 2. Proliferations of germinative…

Differential Diagnosis in Dermatopathology

Images

Surface of dermatofibroma affiliated with follicular germs Surface of superficial basal-cell carcinoma…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Dermatofibroma, hemorrhagic papulo-nodule Kaposi’s sarcoma, hemorrhagic papulo-nodule 1. Poorly circumscribed; border sometimes jagged 1. Well-circumscribed; border smooth 2. Epidermis acanthotic and hyperpigmented 2. Epidermis thinned a…

Differential Diagnosis in Dermatopathology

Images

Dermatofibroma, hemorrhagic papulo-nodule Kaposi’s sarcoma, hemorrhagic papulo-nodule…

Differential Diagnosis in Dermatopathology

Images

Dermatofibroma Desmoplastic Spitz’s nevus…