Search Results for: fibrin

Development of poorly differentiated invasive squamous cell carcinoma in giant Bowen’s disease: a case report with dermatoscopy

Development of poorly differentiated invasive squamous cell carcinoma in giant Bowen’s disease: a case report with dermatoscopy

…es and a vascular pattern, observed as large coiled vessels in linear arrangement intermingled with ulcerations and adherent fibrin crusts (Figure 2). Figure 2. Dermatoscopy of the central region. (A) Linear arrangement of coiled vessels becoming…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ultinucleate, in the wall of an artery and in a contiguous lobule = Temporal arteritis In polyarteritis nodosa, by contrast, fibrin often is present in the wall of the affected artery and the infiltrate of inflammatory cells in the adjacent lobules…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…utrophils is absent, a finding crucial for differentiation of a lesion of urtica from one of leukocytoclastic vasculitis. No fibrin appears in the wall of venules in urtica, unlike the situation in lesions developed fully of leukocytoclastic…

Differential Diagnosis in Dermatopathology

Tuberculoid leprosy vs. Sarcoidosis

A type of small-vessel vasculitis (venulitis) of the skin, occurring especially in the vicinity of the ankle, characterized at first by purpuric macules and patches that, in time, may become hemorrhagic blisters that ulcerate and heal with white,…

Differential Diagnosis in Dermatopathology

Discussions

Dermatitis herpetiformis and bullous pemphigoid share several findings, namely, subepidermal vesiculation, fibrin in subepidermal spaces, and a mix of inflammatory cells, among them lymphocytes and some neutrophils and eosinophils. The changes…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…ften preserved 5. Neutrophils in collections, nuclear “dust of neutrophils,” basophilia of collagen bundles, and fibrin at the tip of dermal papillae are present beneath and at the sides of a blister 5. No neutrophils, basophilia of…

Histologic Diagnosis of Inflammatory Skin Diseases

Persistent pigmented purpuric dermatitis

…e), spongiotic (Doucas and Kapetanakis), and lichenoid (Gougerot-Blum) dermatitis. They do not qualify as vasculitis because fibrin is not present in the wall of venules and thrombi are not found in the lumen of them. Bibliography Bibliography for…

Histologic Diagnosis of Inflammatory Skin Diseases

Disseminated intravascular coagulopathy

…f fibrinogen, platelets, prothrombin, and other factors of coagulation are notable, as well as is elevated split products of fibrin. Cause and mechanism The cause is activation of the coagulation process with consumption of fibrin, platelets, and…