Search Results for: fibrin

Histologic Diagnosis of Inflammatory Skin Diseases

Prurigo pigmentosa

…r “dust” of neutrophils and the presence often of fibrin in the wall of venules. Dermatitis herpetiformis/linear IgA dermatosis: Neutrophils fill dermal papillae and are lodged, along with fibrin, in subepidermal clefts. As a rule, neutro…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ber of thick-walled venules lined by plump endothelial cells, fibrin in the wall of some venules, extravasated erythrocytes, and numerous siderophages + 11.1.1C + 11.1.1D = Acroangiodermatitis  This condition, which is thought to be an expression in…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…e = Temporal arteritis  In polyarteritis nodosa, by contrast, fibrin often is present in the wall of the affected artery and the infiltrate of inflammatory cells in the adjacent lobules of adipocytes is scant. The section pictured comes from a biopsy…

Differential Diagnosis in Dermatopathology

Discussions

…id share several findings, namely, subepidermal vesiculation, fibrin in subepidermal spaces, and a mix of inflammatory cells, among them lymphocytes and some neutrophils and eosinophils. The changes histopathologic enumerated at the outset of this ch…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…his fundamentally small-vessel vasculitis is characterized by fibrin in the wall of venules and thrombi in lumen of them. In addition, there are signs of suppuration, ulceration, and scale-crust. This is but one of several cutaneous manifestations of…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…nt usually 1. No nuclear “dust” of neutrophils 2. Fibrin in and around the wall of venules 2. No fibrin in and around the wall of small vessels 3. No thrombi 3. Thrombi in small vessels 4. Eosinophils present commonly 4. No eosinophils as…

Histologic Diagnosis of Inflammatory Skin Diseases

Persistent pigmented purpuric dermatitis

…t-Blum) dermatitis. They do not qualify as vasculitis because fibrin is not present in the wall of venules and thrombi are not found in the lumen of them. Bibliography Bibliography for persistent pigmented purpuric dermatitis Calnan CD. Lichen aurens…

Histologic Diagnosis of Inflammatory Skin Diseases

Disseminated intravascular coagulopathy

…ophilic material. Laboratory confirmation Decreased levels of fibrinogen, platelets, prothrombin, and other factors of coagulation are notable, as well as is elevated split products of fibrin. Cause and mechanism The cause is activation of the coagul…