Search Results for: hypergranulosis

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…in the groin, which explains why signs of intertrigo, i.e., lichen simplex chronicus in the form of compact orthokeratosis, hypergranulosis, and spinous cell proliferation, are imposed on findings typical of Hailey-Hailey disease. 10.45.7A:…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Inverted Follicular Keratosis, Tricholemmoma, and Desmoplastic Tricholemmoma?

…eccrine ductal epithelium. Parakeratosis is most prominent at the summit of papillations or digitations, infundibula exhibit hypergranulosis marked by coarse clumps of keratohyalin, and dilated tortuous capillaries are present in thin dermal…

Development of poorly differentiated invasive squamous cell carcinoma in giant Bowen’s disease: a case report with dermatoscopy

Development of poorly differentiated invasive squamous cell carcinoma in giant Bowen’s disease: a case report with dermatoscopy

…ith a keratin plug that is visible as a yellow or an orange clod on dermatoscopy. White circles correspond to acanthosis and hypergranulosis in the infundibular epidermis, which in effect is invasion of adnexa and can be a feature of…

Spitz/Reed nevi: a review of clinical-dermatoscopic and histological correlation

Spitz/Reed nevi: a review of clinical-dermatoscopic and histological correlation

…at the right side. (B) Histopathology unveils a junctional asymmetric lesion with epidermal hyperplasia, hyperkeratosis and hypergranulosis exhibiting a focal infiltration of dermal melanophages responsible for the blue-whitish veil seen under…

Differential Diagnosis in Dermatopathology

Discussions

…o conditions have many attributes in common: compact orthokeratosis; dilatation of infundibula by a plug of cornified cells; hypergranulosis of infundibula; uneven psoriasiform acanthosis, coarse bundles of collagen arranged in vertical streaks in a…

Histologic Diagnosis of Inflammatory Skin Diseases

Psoriasis

…ae Psoriasiform acanthosis of variable extent; rete ridges of equal lengths Suprapapillary plates thin slightly Wedge-shaped hypergranulosis, especially in infundibula Compact orthokeratosis Correlation clinicopathologic Papules of psoriasis are…

Differential Diagnosis in Dermatopathology

Discussions

…en planus from all other lichenoid dermatitides are compact orthokeratosis devoid of parakeratosis and wedge-shaped zones of hypergranulosis that form in structures that pass through the epidermis, i.e., acrosyringia and “acrotrichia.”…

Histologic Diagnosis of Inflammatory Skin Diseases

Lupus erythematosus

…brane, and mucin in abundance in the reticular dermis are attributes of lupus erythematosus. Moreover, wedge-shaped zones of hypergranulosis in repeatable pattern typical of lichen planus are not met with as a rule in classic discoid lupus…

Differential Diagnosis in Dermatopathology

Lichen planus vs. Lichen planus-like keratosis

Loss of hair attributable either to the effects of inflammatory cells on follicles or to physiological or mechanical factors in which inflammatory cells play no role. Although the scalp is the site most often affected, any region of the skin that…

Differential Diagnosis in Dermatopathology

Discussions

…atrophic, hypertrophic, bullous), most have in common the following attributes histopathologic: Compact orthokeratosis Focal hypergranulosis in wedge shape Jagged acanthosis Necrotic keratocytes (Civatte bodies, colloid bodies, apoptotic bodies) at…