Histologic Diagnosis of Inflammatory Skin Diseases

Arthropod assaults

Arthropod assaults Synonyms Insect “bite” Bug bite Insect bite reaction Papular urticaria Lichen urticatus Strophulus Presentation stereotypical Age and sex Any age and both sexes Distribution of lesions At times only a single lesion a…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.2.1A: Perivascular dermatitis, spongiotic and slightly psoriasiform + 10.2.1B: Slight edema of the papillary dermis and scale-crust = Nummular dermatitis ┬áChanges such as these are indistinguishable from those of allergic contac…

Histologic Diagnosis of Inflammatory Skin Diseases

Definition of Inflammation in Historical Perspective

The word “inflammation” was introduced about 2,000 years ago by Celsus in one of the eight volumes he devoted to the history of medicine. In the third volume of that monumental work, Celsus mentioned four signs and symptoms he deemed to…

Dermatology Practical & Conceptual

The so-called dysplastic nevus is not dysplastic at all

Editorial In a recent two-part essay entitled “The dysplastic nevus: from historical perspective to management in the modern era” published in the Journal of American Academy of Dermatology, Duffy and Grossman concluded, following compre…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Langerhans’ Cell Granulomatosis?

“The cells of histiocytosis X [HX] have been designated “histiocytes” but the “ordinary” histiocytes encountered in healthy skin, in histiocytoma or various granulomatous processes are devoid of the granules. It could…

Histologic Diagnosis of Inflammatory Skin Diseases

Pattern Analysis in Historical Perspective

In 1963, the year that one of us (A.B.A.) began a residency in dermatology, Walter Lever’s textbook, Histopathology of the Skin, was in its third edition and was deemed, universally, to be “the bible” of dermatopathology. To a firs…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Endothelial Swelling?

“In PLEVA, the more severe form, one observes vascular changes consisting of a pronounced mononuclear infiltrate around capillaries, with the capillaries showing endothelial swelling and permeation of their walls by the infiltrate. This usua…