Differential Diagnosis in Dermatopathology

Differential Diagnosis

Lichen nitidus Lichen striatus 1. In sections from a 4.0 mm punch biopsy specimen, a discrete collection of mononuclear cells of one papilla or in but a few of them; no diffuse involvement 1. In sections from a 4.0 mm biopsy specimen, involvemen…

Histologic Diagnosis of Inflammatory Skin Diseases

Dermatitis herpetiformis

Dermatitis herpetiformis Synonyms During-Brocq disease Duhring’s disease Presentation stereotypical Age and sex Begins usually in young adults, but may appear for the first time in children or in middle-aged persons; no predilection for eith…

Histologic Diagnosis of Inflammatory Skin Diseases

Sebaceous Units

A sebaceous gland, a lipid-producing epithelial structure, develops in the fourth month of fetal life from a protuberance of epithelium that lies between the uppermost protrusion, which represents the future apocrine unit, and the lower bulge, which…

Differential Diagnosis in Dermatopathology

Lichen nitidus vs. Lichen striatus

An inflammatory process that results from the effects of a drug administered systemically, e.g., by ingestion, inhalation, injection, or application rectally, and manifested usually by lesions distributed widely and symmetrically. Any of the many ex…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen planus

Lichen planus Synonyms Lichen ruber planus Lichen ruber Presentation stereotypical Age and sex More common in women, especially young and middle-aged adults Distribution of lesions Flexor surface of forearms and wrists, but no site is exempt. Occu…

Histologic Diagnosis of Inflammatory Skin Diseases

Grover’s disease

Grover’s disease Synonyms Transient acantholytic dermatosis Transitory acantholytic dermatosis Benign papular acantholytic dermatosis Persistent acantholytic dermatosis Presentation stereotypical Age and sex Middle-aged and elderly adults, h…

Histologic Diagnosis of Inflammatory Skin Diseases

Infundibulofolliculitis, disseminate and recurrent

Infundibulofolliculitis, disseminate and recurrent Presentation stereotypical Age and sex Young Africans and African-Americans, especially men Distribution of lesions Widespread Arrangement of lesions Scattered and discrete; equidistant from one ano…

Histologic Diagnosis of Inflammatory Skin Diseases

Incontinentia pigmenti

Incontinentia pigmenti Synonyms Bloch-Sulzberger syndrome Presentation stereotypical Age and sex Lesions in females at birth. Practically never in boys. Distribution of lesions Trunk and extremities Arrangement of lesions Linear, streaks, and whorls…