Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.26.1A: Perivascular dermatitis and peri-infundibulitis, lymphocytes predominant + 10.26.1B: Many thick, brightly eosinophilic elastic fibers beneath and within an infundibular channel. + 10.26.1C + 10.26.1D…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…r epidermis 15. Spongiosis in infundibula often 16. No peri-infundibulitis or perifolliculitis 16. Peri-infundibulitis and perifolliculitis common 17. No eccrine adenitis 17. Eccrine adenitis sometimes 18. Infiltrate of inflammatory cells not a…

Histologic Diagnosis of Inflammatory Skin Diseases

Dermatitis herpetiformis

…n consists of bullae arranged randomly rather than in groups. Infundibulitis (“folliculitis”) is pustular rather than vesicular. Insect “bites” may be disposed in linear fashion, but not usually in clusters; when those lesions…

Histologic Diagnosis of Inflammatory Skin Diseases

Sebaceous Units

…hought to be important in the pathogenesis of the suppurative infundibulitis of acne vulgaris. Although sebaceous glands are apparent readily in sections of tissue of newborn skin, they regress soon afterwards and remain small throughout childhood. I…

Differential Diagnosis in Dermatopathology

Lichen nitidus vs. Lichen striatus

An inflammatory process that results from the effects of a drug administered systemically, e.g., by ingestion, inhalation, injection, or application rectally, and manifested usually by lesions distributed widely and symmetrically. Any of the many ex…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen planus

…tion alopecia, which also presents itself as a lichenoid peri-infundibulitis and perifolliculitis of lymphocytes and ends with alopecia that is permanent. As a rule, the bandlike infiltrate of lymphocytes in traction alopecia does not descend much be…

Histologic Diagnosis of Inflammatory Skin Diseases

Grover’s disease

…resent themselves as papulovesicles and vesicles. Suppurative infundibulitis is characterized by pustules that are pierced by a hair. Scabies favors webs and may be associated with burrows. Findings histopathologic All types Denominators in common fo…

Histologic Diagnosis of Inflammatory Skin Diseases

Infundibulofolliculitis, disseminate and recurrent

…Course Protracted Differential diagnosis clinical Suppurative infundibulitis differs because the basic lesion is a pustule. Findings histopathologic Fully developed Superficial perivascular infiltrate of lymphocytes Spongiosis in infundibula Correl…

Histologic Diagnosis of Inflammatory Skin Diseases

Incontinentia pigmenti

…is not a spongiotic dermatitis; it seems to be a suppurative infundibulitis that houses countless eosinophils, akin to eosinophilic pustular folliculitis of HIV and Ofuji’s disease. Dermatophytes are capable of inducing most of the patterns of…