Histologic Diagnosis of Inflammatory Skin Diseases

Granuloma faciale

…conjunction with venules that house fibrin in their wall. The sequence in which inflammatory cells enter lesions of erythema elevatum diutinum and granuloma faciale is the same, namely, neutrophils, accompanied by plentiful nuclear “dust”…

Dermatology Practical & Conceptual

The order of things and the classification of melanoma

…s science progresses, the era of morphology is fading. The consequence is that organisms and diseases are being reclassified based on molecular findings. With regard to melanoma new mutations are discovered every other week and a new, molecular-based…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Reactive Perforating Collagenosis?

…that sometimes extend well into the reticular dermis. As a consequence of the trauma, which nearly always takes the form of furious scratching, bundles of collagen undergo degeneration and are dispatched from their site original to the skin surface,…

Differential Diagnosis in Dermatopathology

Urticarial reaction to an arthropod assault vs. Urtica

A papular and pustular inflammatory process that is centered in follicles and is distributed mostly in the middle third of the face in both vertical and horizontal directions. Among the varied manifestations of rosacea are innumerable telangiectases…

Differential Diagnosis in Dermatopathology

Discussions

…an insect “bite” is wedge-shaped possibly as a consequence of an arthropod having attacked the skin head-on.. A discrete focus of spongiosis or a spongiotic vesicle marks the actual site of the “bite.” In contrast, spongiosis…

Differential Diagnosis in Dermatopathology

Discussions

…g., larvae of creeping eruption, cercariae of swimmer’s itch, nematocysts of the Portuguese man-of-war, hairs of the puss caterpillar, and spines of sea anemones and coral. When changes in the dermis brought forth by those agents are spotted, c…