Histologic Diagnosis of Inflammatory Skin Diseases

Grover’s disease

…lly developed papules are only slightly scaly because the parakeratosis and scale-crusts are so meager. In contrast, the Darier type is topped by a formidable zone of parakeratosis, often a short column, and, therefore, the papule is keratotic clinic…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Pustular Dermatitis

…rophils of them seemingly programmed to race to mounds of parakeratosis. The presence still of the original stratum corneum with its basket-weave configuration permits the inference that these pustules are but a few days old. Figure 5.310 A&B….

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Overlap Syndromes?

…ocytes, the jagged hyperplasia of the epidermis, and the hyperkeratosis merely resemble findings in lichen planus. In lichenoid discoid lupus erythematosus, in contrast to lichen planus, the infiltrate of lymphocytes tends to be deep as well as super…

Differential Diagnosis in Dermatopathology


Seborrheic keratosis of the acanthotic type and eccrine poroma are both benign, epithelial, exo-endophytic neoplasms comprised mostly of small, round (basaloid) cells. Melanocytes may be scattered among keratocytes in both conditions. Seborrheic ker…

Histologic Diagnosis of Inflammatory Skin Diseases

Definition of Inflammation in Historical Perspective

…apable of inducing an inflammatory response, e.g., seborrheic keratosis that in the face of an infiltrate of lymphocytes becomes a lichen planus-like keratosis and a certain kind of compound melanocytic nevus that, consequent to effects of lymphocyte…