Histologic Diagnosis of Inflammatory Skin Diseases

Lichen sclerosus et atrophicus

…histopathologic Early Superficial perivascular infiltrate of lymphocytes Patchy lichenoid infiltrate of lymphocytes in conjunction with vacuolar alteration obscuring the dermoepidermal junction Markedly altered, pale collagen in the papillary dermi…

Differential Diagnosis in Dermatopathology

Discussions

…share some findings histopathologic, including the presence of lymphocytes as solitary units, as well as in collections, in the epidermis, spongiosis, acanthosis at times, parakeratosis in which serum resides, and a perivascular infiltrate in which l…

Differential Diagnosis in Dermatopathology

Discussions

…in the upper part of the dermis, it often containing abnormal lymphocytes and episodically eosinophils. Many of the abnormal lymphocytes have cerebriform nuclei. Mitotic figures may be seen within lymphocytes. For these reasons, distinguishing histo…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…tes are huddled around venules; near the end of it, only a few lymphocytes are found there. 10.111.5A: Perivascular and interstitial dermatitis + 10.111.5B: Lymphocytes and eosinophils around a venule and eosinophils and a few neutrophils i…

Histologic Diagnosis of Inflammatory Skin Diseases

Polymorphous light eruption

…superficial or superficial and deep perivascular infiltrate of lymphocytes Fully developed Moderately dense superficial and deep perivascular infiltrate of lymphocytes Marked edema of the papillary dermis Subepidermal vesiculation secondary to edem…

Histologic Diagnosis of Inflammatory Skin Diseases

Subcutaneous T-cell lymphoma

…Fully developed Dense patchy or diffuse infiltrates of small lymphocytes, plasma cells, neutrophils, eosinophils, and abnormal lymphocytes in lobules of the subcutaneous fat; some abnormal lymphocytes in mitosis common Phagocytosis of erythrocytes…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…tion here. 10.28.6A: Vesicular dermatitis, subepidermal, lymphocytes predominant + 10.28.6B: Dense perivascular and interstitial infiltrates of lymphocytes mostly, fibrin in association with lymphocytes in the subepidermal blister, and a ra…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Parapsoriasis?

…e lesions are characterized by patchy lichenoid infiltrates of lymphocytes associated with wiry bundles of collagen arrayed haphazardly in the upper part of the dermis, by an epidermis peppered in loci by lymphocytes in conjunction with scant spongio…