Search Results for: macule

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Precursor Lesions of Melanoma?

…lderly people. Its precursor lesion, the lentigo maligna (Hutchinson’s melanotic freckle), is an irregularly pigmented macule which expands slowly.” Weedon D. Lentigines, nevi and melanomas. In: Skin Pathology. 2nd ed. London: Churchill…

Differential Diagnosis in Dermatopathology

Discussions

…well-developed “lentigo maligna” usually has gradations of color from light brown to black within it. Not every macule of melanoma on sun-battered skin of a face eventuates in a patch. Some progress to become a papule and even a nodule…

Differential Diagnosis in Dermatopathology

Dermatofibroma vs. Dermatofibrosarcoma protuberans

A hamartoma of epidermis, epithelial structures of adnexa, and presumably dermal elements, typified, when fully formed, by a papillated or verrucous yellowish plaque situated usually on the scalp. The condition may present itself as a solitary…

Differential Diagnosis in Dermatopathology

Pyogenic granuloma, fully developed vs. Kaposi’s sarcoma, nodular

A hamartoma of epidermis, epithelial structures of adnexa, and presumably dermal elements, typified, when fully formed, by a papillated or verrucous yellowish plaque situated usually on the scalp. The condition may present itself as a solitary…

Review of Atlas of Vulvar Pathology. 3rd ed. by EJ Wilkinson, IK Stone

Review of Atlas of Vulvar Pathology. 3rd ed. by EJ Wilkinson, IK Stone

…and not in the chapter on malignant tumors. A melanoma certainly can present as a papular lesion, but it can also occur as a macule, a plaque or an ulcer and it certainly is a malignant tumor. Another evident flaw in this classification is…

Histologic Diagnosis of Inflammatory Skin Diseases

Vitiligo

…pigmentation, and lesions are scaly. Piebaldism is congenital, spares the midline, and is associated with poliosis. Ash-leaf macule of epiloia has a characteristic shape and is present in a setting of other defects congenital. Findings…

Differential Diagnosis in Dermatopathology

Discussions

…that intersect the angiomatous elements and, at last, involutes by progressive fibrosis. Kaposi’s sarcoma begins as a macule or patch that is characterized histopathologically by an increase in number of endothelium-lined spaces with jagged…

Differential Diagnosis in Dermatopathology

Discussions

…extravasation of red blood cells; a brownish papule when hyperpigmentation of the epidermis is striking; and resolution as a macule characterized by hypopigmentation in the center and hyperpigmentation at the periphery when the lesion has…