Differential Diagnosis in Dermatopathology

Dermatofibroma vs. Dermatofibrosarcoma protuberans

Circular orange-red-blue macule(s) or patch(es) that often becomes a papule(s) or plaque(s) and vesiculates, healing with hyperpigmentation, and that occurs repeatedly at the very same cutaneous and/or mucous membrane site(s), especially the genital…

Differential Diagnosis in Dermatopathology

Pyogenic granuloma, fully developed vs. Kaposi’s sarcoma, nodular

Circular orange-red-blue macule(s) or patch(es) that often becomes a papule(s) or plaque(s) and vesiculates, healing with hyperpigmentation, and that occurs repeatedly at the very same cutaneous and/or mucous membrane site(s), especially the genital…

Dermatology Practical & Conceptual

Review of Atlas of Vulvar Pathology. 3rd ed. by EJ Wilkinson, IK Stone

The cover Figure 1. Wilkinson EJ, Stone IK. Atlas of Vulvar Pathology. 3rd ed. Philadelphia: Lippincott Williams & Wilkins, 2012. ISBN: 1451132182.274 pages. List price: $164.99. Review by Fran├žois Milette This atlas of vulvar disease (sic) is…

Histologic Diagnosis of Inflammatory Skin Diseases

Vitiligo

Vitiligo Synonyms Achroma vitiligo Presentation stereotypical Age and sex Young adults and women especially Distribution of lesions Localized, segmental, or widespread; often symmetric Individual lesions Macules and patches Course Protracted usually…

Differential Diagnosis in Dermatopathology

Discussions

Both pyogenic granuloma and Kaposi’s sarcoma consist of proliferations of endothelial cells, and both are hyperplasias. In most instances, papules and nodules of Kaposi’s sarcoma are differentiated easily by microscopy conventional from…

Differential Diagnosis in Dermatopathology

Discussions

Despite the differences biologic between dermatofibroma (an inflammatory process) and desmoplastic (fibrosing, largely intradermal) Spitz’s nevus (a benign neoplastic process), the two conditions have many attributes morphologic in common. Bot…

Differential Diagnosis in Dermatopathology

Discussions

Ascendency of the shave biopsy technique by dermatologists has created bedeviling problems for dermatopathologists and general pathologists because that slice (often sliver) method does not permit architectural patterns of skin diseases to be studie…

Differential Diagnosis in Dermatopathology

Dermatofibroma vs. Desmoplastic Spitz’s nevus

Circular orange-red-blue macule(s) or patch(es) that often becomes a papule(s) or plaque(s) and vesiculates, healing with hyperpigmentation, and that occurs repeatedly at the very same cutaneous and/or mucous membrane site(s), especially the genital…

Differential Diagnosis in Dermatopathology

Discussions

Dermatofibroma and dermatofibrosarcoma protuberans are lesions made up of dense diffuse infiltrates of mesenchymal cells in company with bundles of collagen, the two together occupying at least much of the thickness of the dermis and sometimes part…